Grants and Grant Recipients
For over 30 years, AAMDSIF has provided research grants totaling in excess of $5.5 million to an international group of more than 100 researchers to help advance the understanding and treatment of aplastic anemia , myelodysplastic syndromes (MDS), and paroxysmal nocturnal hemoglobinuria (PNH).
The two-year grants have helped bring forth new insights into the causes and therapeutic approaches for these diseases. These grantee profiles present the grantees by year the awards were granted, and a summary of their grant-funded research projects.
Grant Year: 2010
Muneyoshi Futami, MD, PhD
Harold Spielberg Research Fund
Ramon V. Tiu, MD
Torry Yahn Research Fund
Grant Year: 2009
Regis Peffault deLatour, MD, PhD
PNH Research and Support Foundation
Archibald S. Perkins, MD, PhD
Harold Spielberg Research Fund
Grant Year:
Simona Pagliuca, MD
Arthur Kunofsky Research Fund
RACE is a phase III randomized study initiated in 2015 whose aim was to evaluate whether the standard first-line therapy for severe aplastic anemia (anti-thymoglobuline and cyclosporine) could be improved by the addition of eltrombopag, a small molecule previously showing a promising effect in stimulating hematopoiesis.
The purpose of the present translational research was to understand how the aberrant immune response characterizing aplastic anemia could be modified by the introduction of eltrombopag.
RACE trial has recently concluded and results are under publication.