MDS Causes
Doctors can’t identify a specific cause in 9 out of 10 MDS cases. These are called “de novo” MDS, meaning arising without a known cause.
diagnosis
Robert A. Brodsky, MD
Institution
Johns Hopkins
Physician Status
accepting new patients
Primary Disease Area of Focus
Aplastic Anemia
About
Earlier this summer, AAMDSIF called for research proposals addressing Paroxysmal Nocturnal Hemoglobinuria (PNH). Robert A. Brodsky, MD, is the Johns Hopkins Family Professor of Medicine and Oncology and Director of the Division of Adult Hematology. He has a long track record of funded research through the NIH and through foundation grants, and serves as the Director of the Johns Hopkins Hematology Fellowship program, as well as the PI for the Johns Hopkins T32 in hematology and co-PI of a K12 in benign hematology. His focus on PNH and interest in translational medicine led his laboratory to
“Mom, it’s too late. I’m dying.”
My husband Rick and I knew Jake was not feeling well. He kept denying it and saying he was fine. A bloody nose scared me, and then I remembered how my brother-in-law had them as a child and thought it was hereditary. Then his high school said he had another. He began to ask us if he looked pale. We said that he did. He also was coughing and seemed lethargic. We encouraged him to go to the doctor, but he said he was fine.
Types of Research Articles Part I
This article describes some of the most common types of research articles published in medical journals. Medical journals publish many types of articles not discussed here. A comprehensive list is available from the National Library of Medicine.
Research articles can be primary or secondary. A primary research article describes the design, methods, and results of a study. A secondary research article is a review of at least two primary research articles.
Primary articles
Disease Won't Run My Life
My odyssey with bone marrow failure bone marrow failure: A condition that occurs when the bone marrow stops making enough healthy blood cells.
Why Research is Important: Understanding Research Articles Part I
The medical care we enjoy today is built upon decades of effort by physicians, researchers, and other medical professionals investigating the causes of, and potential treatments for disease.
Finding a Stem Cell Donor
When should I start looking for a suitable donor?
If your doctor thinks you may be a candidate for a bone marrow bone marrow: The soft, spongy tissue inside most bones.
Biting into the Elephant
I believe that a story is the shortest distance between two people. While this is my story, it is not just mine, and I did not do any of this alone. In April 1983, my husband Joe and I were 25 years old and attending to the required pre-marital blood work. Next thing we knew, we were sitting in a doctor’s office because my blood counts were abnormally low. They told us there was something wrong, but they didn’t know what it was.
End-of-Life Resources
The Aplastic Anemia Aplastic Anemia: (ay-PLASS-tik uh-NEE_mee-uh) A rare and serious condition in which the bone marrow fails to make enough blood cells - red blood cells, whit
Lukasz Gondek, M.D., Ph.D.
Institution
Johns Hopkins University School of Medicine
Physician Status
accepting new patients
Primary Disease Area of Focus
Acute Myeloid Leukemia (AML)
Myelodysplastic Syndromes (MDS)
About
Dr. Gondek is a current Evans Fellow at Johns Hopkins University in the Department of Oncology, working with Dr. Amy Dezern on research related to signaling pathways in MDS stem cells. Dr. Gondek explained that the mechanism of progression in MDS is poorly understood, and he hopes through his work to clarify some of the factors that contribute to progression. He is the Principal Investigator on one pilot project currently underway within the MDS Clinical Research Consortium, working with a particular signaling pathway named the Hedgehog pathway. Dr. Gondek describes the Hedgehog (Hh) pathway