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aplastic anemia

Maria Baer, MD

Baer, Maria
Director, Hematologic Malignancies Program
University of Maryland Greenebaum Comprehensive Cancer Center

Maria Baer joined the University of Maryland Marlene and Stewart Greenebaum Cancer Center in Baltimore, Maryland in 2007 as director of hematologic malignancies and professor of medicine and molecular medicine, University of Maryland School of Medicine. She previously served as chief of the leukemia section at Roswell Park Cancer Institute and professor of medicine and associate professor of molecular pharmacology and cancer therapeutics at the University at Buffalo School of Medicine and Biomedical Sciences in Buffalo, New York.

Online Profile: 
https://www.umms.org/find-a-doctor/profiles/dr-maria-baer-md-1700881802

A randomized comparison of cyclophosphamide vs. reduced dose cyclophosphamide plus fludarabine for allogeneic hematopoietic cell transplantation in patients with aplastic anemia and hypoplastic myelodysplastic syndrome.

Author(s): 
Kim H, Lee JH, Joo YD, Bae SH, Hyun MS, Lee JH, Kim DY, Lee WS, Ryoo HM, Kim MK, Park JH, Lee KH; Cooperative Study Group A for Hematology (COSAH).
Primary Author: 
Kim H
Journal Title: 
Ann Hematol.
Original Publication Date: 
Apr 2012

Abstract

Bone Marrow Disease(s): 

Kyle Malmstrom – Saved by Identical Twin, Young Aplastic Anemia Survivor Literally Brings Comfort to Others

Person's Name: 
Kyle Malmstron

Written by Kimberly Malmstrom

Our son, Kyle, was a normal active 11-year-old who enjoyed climbing trees, swimming, and running. He loved to run around and play with his friends.  The first week of school last fall was normal for Kyle.  He was excited to see friends and meet his new sixth grade teachers. However, throughout that week, he developed large bruises. Some had known causes - others did not.  

Bone Marrow Disease(s): 
Content source: 
web exclusive

Classification of childhood aplastic anemia and myelodysplastic syndrome

Author(s): 
Niemeyer CM, Baumann I
Primary Author: 
Niemeyer CM
Journal Title: 
Hematology Am Soc Hematol Educ Program
Original Publication Date: 
Dec 2011

Hypoplastic BM disorders in children and adolescents comprise a broad spectrum of disorders. Acquired severe

Bone Marrow Disease(s): 

Long-term follow-up after allogeneic stem cell transplantation in patients with severe aplastic anemia after cyclophosphamide plus antithymocyte globulin conditioning

Author(s): 
Konopacki J, Procher R, Robin M, Bieri S, Cayuela JM, Larghero J, Xhaard A, Andreoli AL, Dhedin N, Petropoulou AD, Rodriguez-Otero P, Ribaud P, Moins-Teisserenc H, Carmagnat M, Toubert A, Chalandon Y, Socie' G, Peffault de Latour R
Primary Author: 
Konopacki J
Journal Title: 
Haematologica
Original Publication Date: 
Dec 2011

Background. Due to increased rates of secondary solid organ cancer in patients with severe

Bone Marrow Disease(s): 

Functional characterization of CD4+ T cells in aplastic anemia

Author(s): 
Kordasti S, Marsh J, Al-Khan S, Jiang J, Smith A, Mohamedali A, Abellan PP, Veen C, Constantini B, Kulasekararaj AG, Benson-Quarm N, Seidl T, Mian SA, Farzaneh F, Mufti GJ
Primary Author: 
Kordasti S
Journal Title: 
Blood
Original Publication Date: 
Dec 2011

he role of CD4(+) T-cells in the pathogenesis of AA is not well characterized. The focus of this study is to investigate the role of CD4(+) T-cells in AA with particular emphasis on CD4(+) regulatory and effector T-cell subsets and correlation with disease severity. 63 patients(48 at diagnosis) with acquired AA were studied. Numbers of Th1 and Th2-cells were significantly higher in AA compared with age matched healthy donors (HDs) (p=0.03) (p=0.006).

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