Survival After Immunosuppressive Therapy in Children with Aplastic Anemia
OBJECTIVE:
To determine the survival of children ?18y, treated with immunosuppresive therapy (IST) using equine antithymocyte globulin (e-ATG) and cyclosporine(CsA).
DESIGN:
Prospective data entry as per a specified format.
SETTING:
Tertiary care hospital.
PATIENTS:
From January 1998 to December 2009, 40 children were diagnosed with acquired aplastic anemia; 33 patients, who received IST, were analyzed. 31 children (94%) received one course of e-ATG and CsA. 2 patients (6%) received two courses of ATG.
INTERVENTION:
Immunosuppressive therapy using equine ATG and cyclosporine.
MAIN OUTCOME MEASURES:
Overall response and overall survival.
RESULTS: