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Clinical and Genomic-Based Decision Support System to Define the Optimal Timing of Allogeneic Hematopoietic Stem-Cell Transplantation in Patients With Myelodysplastic Syndromes

Author(s): 
Tentori CA, Gregorio C, Robin M, Gagelmann N, Gurnari C, Ball S, Caballero Berrocal JC, Lanino L, D'Amico S, Spreafico M, Maggioni G, Travaglino E, Sauta E, Meggendorfer M, Zhao LP, Campagna A; GenoMed4All, Synthema, GESMD, FISIM, and EuroBloodNET;
Primary Author: 
Tentori CA
Journal Title: 
Journal of Clinical Oncology
Original Publication Date: 
May 2024

Purpose: Allogeneic hematopoietic stem-cell transplantation (HSCT) is the only potentially curative treatment for patients with

Bone Marrow Disease(s): 

Romiplostim for Treatment of Children and Young Adults With Severe Aplastic Anemia and Myelodysplastic Syndrome

Author(s): 
Sharathkumar A, Carr J, Claassen D, Syrbu S, Bhagavathi S, Al-Huniti A, Modi A, Bates M, Mott SL
Primary Author: 
Sharathkumar A
Journal Title: 
Journal of Pediatric Hematology/Oncology
Original Publication Date: 
May 2024

Thrombopoietin receptor agonists (TPO-RAs) induce trilineage hematopoiesis under conditions with acquired hematopoietic failure.

Bone Marrow Disease(s): 

Treatment of newly diagnosed severe aplastic anemia in children: Evidence-based recommendations

Author(s): 
Shimano KA, Rothman JA, Allen SW, Castillo P, de Jong JLO, Dror Y, Geddis AE, Lau BW, McGuinn C, Narla A, Overholt K, Pereda MA, Sharathkumar A, Sasa G, Nakano TA, Myers K, Gloude NJ, Broglie L, Boklan J
Primary Author: 
Shimano KA
Journal Title: 
Pediatric Blood & Cancer
Original Publication Date: 
May 2024

Severe

Bone Marrow Disease(s): 

Hypomethylating agents are associated with high rates of hematologic toxicity in patients with secondary myeloid neoplasms developing after acquired aplastic anemia

Author(s): 
Connor MP, Prathapa N, Frey NV, Gill SI, Hexner EO, Bruno XJ, Lai CE, Loren AW, Luger SM, Matthews AH, McCurdy SR, Perl AE, Porter DL, Zeringue A, Oved JH, Olson TS, Pratz KW, Babushok DV
Primary Author: 
Connor MP
Journal Title: 
Haematologica
Original Publication Date: 
Apr 2024
Bone Marrow Disease(s): 

Alternative donor transplantation for severe aplastic anemia: a comparative study of the SAAWP EBMT

Author(s): 
Montoro J, Eikema DJ, Tuffnell J, Potter V, Kałwak K, Halkes CJJ, Kulagin A, Collin M, Wynn RF, Robinson S, Nicholson E, Sengeloev H, Halahleh K, Skorobogatova E, Sanz J, Passweg JR, Mielke S, Ryhänen SJ, Carpenter B, Gedde-Dahl T, Tholouli E, Fanin R
Primary Author: 
Montoro J
Journal Title: 
Blood
Original Publication Date: 
Apr 2024

Selecting the most suitable alternative donor becomes challenging in severe

Bone Marrow Disease(s): 

Modified Delphi Panel Consensus Recommendations for Management of Severe Aplastic Anemia

Author(s): 
Babushok DV, DeZern AE, de Castro C, Rogers ZR, Beenhouwer D, Broder MS, Fanning S, Gibbs SN, Hanna R, Maciejewski JP, Scott BL, Tantravahi SK, Wlodarski MW, Yermilov I, Patel BJ
Primary Author: 
Babushok DV
Journal Title: 
Blood Advances
Original Publication Date: 
Apr 2024

Severe

Bone Marrow Disease(s): 

Early transfusion patterns improve the Molecular International Prognostic Scoring System (IPSS-M) prediction in myelodysplastic syndromes

Author(s): 
Creignou M, Bernard E, Gasparini A, Tranberg A, Todisco G, Moura PL, Ejerblad E, Nilsson L, Garelius H, Antunovic P, Lorenz F, Rasmussen B, Walldin G, Mortera-Blanco T, Jansson M, Tobiasson M, Elena C, Ferrari J, Gallì A, Pozzi S, Malcovati L, Edgren G
Primary Author: 
Creignou M
Journal Title: 
Journal of Internal Medicine
Original Publication Date: 
Apr 2024

Background: The Molecular

Bone Marrow Disease(s): 

Treatment of Myelodysplastic Syndromes for Older Patients: Current State of Science, Challenges, and Opportunities

Author(s): 
Kewan T, Stahl M, Bewersdorf JP, Zeidan AM
Primary Author: 
Kewan T
Journal Title: 
Current Hematologic Malignancy Reports
Original Publication Date: 
Apr 2024

Purpose of review: 

Bone Marrow Disease(s):