myelodysplastic syndromes (MDS) | Aplastic Anemia & MDS International Foundation

myelodysplastic syndromes (MDS)

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Defining the Boundary Between Myelodysplastic Syndromes and Myeloproliferative Neoplasms

Author(s): 
Loghavi S, Wang SA
Primary Author: 
Loghavi S
Journal Title: 
Surgical Pathology Clinic
Original Publication Date: 
Jul 2019

In this article we provide a practical and comprehensive review of myeloid neoplasms with overlapping myelodysplastic (MDS) and myeloproliferative (MPN) features, with emphasis on recent updates in classification, particularly the utility of morphologic, cytogenetic, and molecular findings in better defining and classifying these disease entities.

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RBC transfusion independence among lower risk MDS patients receiving hypomethylating agents: a population-level analysis

Author(s): 
Zeidan AM, Zhu W, Stahl M, Wang R, Huntington SF, Giri S, Podoltsev NA, Gore SD, Ma X, Davidoff AJ
Primary Author: 
Zeidan AM
Journal Title: 
Leukemia & Lymphoma
Original Publication Date: 
Jun 2019

Most patients with lower risk

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A genomics-informed computational biology platform prospectively predicts treatment responses in AML and MDS patients

Author(s): 
Drusbosky LM, Singh NK, Hawkins KE, Salan C, Turcotte M, Wise EA, Meacham A, Vijay V, Anderson GG, Kim CC, Radhakrishnan S, Ullal Y, Talawdekar A, Sikora H, Nair P, Khanna-Gupta A, Abbasi T, Vali S, Guha S, Farhadfar N, Murthy HS
Primary Author: 
Drusbosky LM
Journal Title: 
Blood Advances
Original Publication Date: 
Jun 2019

Patients with

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Guadecitabine (SGI-110) in patients with intermediate or high-risk myelodysplastic syndromes: phase 2 results from a multicentre, open-label, randomised, phase 1/2 trial

Author(s): 
Garcia-Manero G, Roboz G, Walsh K, Kantarjian H, Ritchie E, Kropf P, O'Connell C, Tibes R, Lunin S, Rosenblat T, Yee K, Stock W, Griffiths E, Mace J, Podoltsev N, Berdeja J, Jabbour E, Issa JJ, Hao Y, Keer HN, Azab M, Savona MR
Primary Author: 
Garcia-Manero G
Journal Title: 
The Lancet Haematology
Original Publication Date: 
Jun 2019

BACKGROUND:

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The National MDS Natural History Study: design of an integrated data and sample biorepository to promote research studies in myelodysplastic syndromes

Author(s): 
Sekeres MA, Gore SD, Stablein DM, DiFronzo N, Abel GA, DeZern AE, Troy JD, Rollison DE, Thomas JW, Waclawiw MA, Liu JJ, Al Baghdadi T, Walter MJ, Bejar R, Gorak EJ, Starczynowski DT, Foran JM, Cerhan JR, Moscinski LC
Primary Author: 
Sekeres MA
Journal Title: 
Leukemia & Lymphoma
Original Publication Date: 
May 2019

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