David Young, MD, PhD

David Young, M-D , P-h-D
Position / Title
Associate Research Physician
Institution
NIH

Dr. Young is a board-certified Pediatrician and Pediatric Hematologist: (hee-muh-TOL-uh-jist) A doctor who specializes in treating blood diseases and disorders of blood producing organs. and Oncologist: (on-KAH-luh-jist) A doctor who specializes in the treatment and prevention of cancer. who studies the genetics, molecular biology, and clinical management and treatment of bone marrow failure: A condition that occurs when the bone marrow stops making enough healthy blood cells. The most common of these rare diseases are aplastic anemia, myelodysplastic syndromes (MDS) and paroxysmal nocturnal hemoglobinuria (PNH). Bone marrow failure can be acquired (begin any time in life) or can be… syndromes, myeloid malignancies, and other genetic disorders. He oversees clinical trials: Clinical research is at the heart of all medical advances, identifying new ways to prevent, detect or treat disease. If you have a bone marrow failure disease, you may want to consider taking part in a clinical trial, also called a research study. Understanding Clinical Trials Clinical… in aplastic anemia: (ay-PLASS-tik uh-NEE_mee-uh) A rare and serious condition in which the bone marrow fails to make enough blood cells - red blood cells, white blood cells, and platelets. The term aplastic is a Greek word meaning not to form. Anemia is a condition that happens when red blood cell count is low. Most… and Diamond-Blackfan anemia: A rare form of pure red cell aplasia that can be passed down from parent to child. Diamond-Blackfan anemia (DBA) is characterized by low red blood cell counts detected in the first year of life. Some people with DBA have physical abnormalities such as small head size, low frontal hairline, wide-set… while also working with non-human primate models of disease and preclinical development. He also serves as the Medical Director for the RUNX1 Natural History Program of the National Human Genome Research Institute.

Dr. Young received a B.Sc. from the University of Notre Dame, studying the structure and synthesis of novel antineoplastic agents isolated from natural sources, while also working as a laboratory assistant examining the effects of dietary phytoestrogens in a rat model of prostate cancer. He then completed his MD and PhD in Cancer Biology at the University of Chicago studying the genetics and molecular biology of the therapy-related myeloid neoplasms. After a pediatric internship and residency at Hasbro Children’s Hospital of the Brown University Alpert School of Medicine, he trained in the joint Johns Hopkins-NIH Pediatric Hematology/Oncology Fellowship where he studied the biology and treatment of FLT3-mutated acute myeloid leukemia: (uh-KYOOT my-uh-LOYD loo-KEE-mee-uh) A cancer of the blood cells. It happens when very young white blood cells (blasts) in the bone marrow fail to mature. The blast cells stay in the bone marrow and become to numerous. This slows production of red blood cells and platelets. Some cases of MDS become… . He joined the Translational Stem Cell Biology Branch of the National Heart, Lung, and Blood Institute in 2018 where he has developed preclinical, non-human primate models for cellular therapeutics, marrow diseases. He also conducts laboratory research into hematopoiesis: (hi-mat-uh-poy-EE-suss) The process of making blood cells in the bone marrow. and marrow failure.

Practice Location

Bethesda, MD 90892
United States