Aplastic Anemia

sirolimus

A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS.

Dr. Austin Kulasekararaj

Institution
King’s College Hospital, London
Physician Status
available for consultation
Primary Disease Area of Focus
Aplastic Anemia
Myelodysplastic Syndromes (MDS)
Paroxysmal Nocturnal Hemoglobinuria (PNH)
About
Dr. Austin Kulasekararaj is a hematologist at King’s College Hospital, London. He has trained and worked at King's since 2004, undertaking research in molecular pathogenesis of MDS and aplastic anemia. He specializes in bone marrow failures, myeloid malignancies, and allogeneic bone marrow transplantation. Dr. Kulasekararaj also leads the King's PNH Centre, which is one of two NHS England-commissioned highly specialized services for PNH.

Jay Yang, MD

Institution
Karmanos Cancer Institute
Physician Status
accepting new patients
Primary Disease Area of Focus
Acute Myeloid Leukemia (AML)
Aplastic Anemia
Myelodysplastic Syndromes (MDS)
Myeloproliferative Neoplasms (MPN)

"I Chose Life" - Debra Reflects on Three Years of Challenges with Aplastic Anemia

“Your blood counts are nearly nonexistent,” the doctor said. 

Before this moment, Debra considered herself to be generally healthy, just tiring easily.  She assumed the cause was the big project at work on top of a host of family and volunteer activities, or perhaps issues with her blood pressure. It was autumn of 2017.

Swapna Thota, MD

Institution
University of Tennessee
Physician Status
accepting new patients
Primary Disease Area of Focus
Acute Myeloid Leukemia (AML)
Aplastic Anemia
Myelodysplastic Syndromes (MDS)
Myeloproliferative Neoplasms (MPN)
Paroxysmal Nocturnal Hemoglobinuria (PNH)
About
As a physician caring for patients with acute leukemias and related disorders, I have a sustained focus on translational research in hematologic malignancies. Genomic sequencing technology revolutionized our understanding of cancer biology. My research focuses on exploring the dynamic changes of tumor immune microenvironment with clonal evolution of myeloid malignancies. Targeting inflammaging of bone marrow to impede clonal evolution is my ultimate professional goal and there by improve the survival rate for leukemia patients. My long-term goal is to develop potentially less toxic targeted

This is Your Brain on (Chemo) Drugs - Summer 2021 Conference

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Topic(s)
Acute Myeloid Leukemia (AML)
Aplastic Anemia
Bone Marrow Transplant
Living Well with Bone Marrow Failure
Managing Your Treatment
Myelodysplastic Syndromes (MDS)
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Pediatric Bone Marrow Failure Diseases
Related Bone Marrow Failure Diseases and Malignancies
Presenter(s)
Jorg Dietrich, MD, PhD
Dr. Jorg Dietrich will help patients and their loved ones understand the chemistry and biology behind what happens to patient brains when chemotherapy and other treatments are introduced. This is a great session for caregivers, family members and patients.

Dr. Elizabeth Bowhay-Carnes

Institution
UT Health - San Antonio
Physician Status
accepting new patients
Primary Disease Area of Focus
Acute Myeloid Leukemia (AML)
Aplastic Anemia
Myelodysplastic Syndromes (MDS)
Myeloproliferative Neoplasms (MPN)
Paroxysmal Nocturnal Hemoglobinuria (PNH)
About
Dr. Elizabeth Bowhay-Carnes is a Texas native and passionate about serving the people of her home community. She earned her bachelors of science degree in biochemistry from the University of Texas at Austin, followed by work with the MD Anderson Cancer Center Umbilical Cord Blood Bank in Houston. She received her medical doctorate from UT Health San Antonio and completed her residency in internal medicine and fellowship in hematology and medical oncology at the UT Health Science Center. She joined UT Health San Antonio MD Anderson Cancer Center in 2016 as Director of the Adult Non-Malignant

Dr. Amy Duffield

Institution
Mount Sinai Medical Center
Physician Status
available for consultation
Primary Disease Area of Focus
Acute Myeloid Leukemia (AML)
Aplastic Anemia
Chronic Lymphocytic Leukemia (CLL)
Chronic Myelomonocytic Leukaemia (CMML)
Myelodysplastic Syndromes (MDS)
Myeloproliferative Neoplasms (MPN)
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Pure Red Cell Aplasia (PRCA)
About
Dr. Duffield is a board-certified hematopathologist, specializing in the diagnosis of cancers that arise in the bone marrow and lymphoid tissues. She completed a pathology residency and hematopathology fellowship at the Johns Hopkins Hospital and joined the faculty of Johns Hopkins in 2010. In 2020, she joined Memorial-Sloan Kettering to become a member of the Hematopathology Service.

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