Acute Myeloid Leukemia (AML)

Venetoclax and azacitidine in untreated patients with therapy-related acute myeloid leukemia, antecedent myelodysplastic syndromes or chronic myelomonocytic leukemia

Original Publication Date
Article Source
External Web Content
Dear Editor, Secondary acute myeloid leukemia (sAML), a subset of AML, may arise from antecedent hematologic disorders (antecedent myelodysplastic syndrome or chronic myelomonocytic leukemia [A-MDS/CMML]) or complication of prior cytotoxic chemotherapy or radiation therapy…

2025 AAMDSIF Bone Marrow Failure Summit Acute Myeloid Leukemia Expert Panel

Thumbnail for video Watch Now

Topic(s)
Acute Myeloid Leukemia (AML)
Presenter(s)
Mikkael Sekeres, MD, MS
Kah Poh (Melissa) Loh, MBBCh BAO, MS, FACCC
Christopher Hourigan, DM, DPhil, FRCP
Noa Holtzman, MD
Watch AML experts at the 2025 AAMDSIF Bone Marrow Failure Summit translate and discuss the latest science to advance patient outcomes. This session is moderated by Mikkael Sekeres, MD, MS from the University of Miami. Session Topics: HMA + Ven vs. 7+3 vs. liposomal cytarabine…

Maintenance Therapy in AML: What Is the Future Potential?

Original Publication Date
Article Source
External Web Content
ABSTRACT Over the last decade, there have been significant advancements in the treatment for patients with acute myeloid leukemia (AML) including the addition of novel, targeted agents to intensive or nonintensive chemotherapy regimens. However, despite this, the majority of…

Therapeutic Advances and Future of Therapy in Acute Myeloid Leukemia

Original Publication Date
Article Source
External Web Content
Significant progress in the characterization of molecular pathogenic events in acute myeloid leukemia (AML) has led to better characterization of prognosis and identification of subsets that are more likely to benefit from currently available strategies. Furthermore, deciphering…

Diagnosis of TP53-mutated myeloid disease by the ICC and WHO fifth edition classifications

Original Publication Date
Article Source
External Web Content
Key Points The ICC and WHO5 differently classify 64% of TP53-mutated disease due to distinct criteria for multihit TP53 mutations and TP53-mutated AML. MDS with a single TP53 mutation and CK is similar to MDS with biallelic TP53 abnormalities, whereas TP53-mutated AML is distinct…

ACROBAT interim results support AlloHeme for relapse prediction in AML, MDS

Original Publication Date
Article Source
External Web Content
Interim results of the ACROBAT study suggest that increasing microchimerism and loss of complete chimerism may indicate relapse risk in patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). The findings were presented in an oral abstract1 at the 2025…

Make Your Voice Count!

Join us in endorsing the recent appeal to Congress with the following actions. Your voice is important to continue these services for patients and provide opportunities for researchers to find the cures.

Read the letter to Congress from Research!America, with AAMDSIF and 600 other organizations, here.

Letter on the Bipartisan Senate FY25 Labor-HHS-Education Appropriations Bill

Original Publication Date
Article Source
Coalition Action
AAMDSIF is Taking a Stand for NIH Research Research programs led by the National Institutes of Health (NIH) forge the way for life-saving new treatments for rare diseases such as aplastic anemia, MDS, and PNH. With clinical research locations throughout the U.S., researchers and…
Subscribe to Acute Myeloid Leukemia (AML)

Website Feedback

Please use this feedback form to report website issues only. For other issues concerning patients and families, please email help@aamds.org or use the Patient and Family Helpline here.