Grants and Grant Recipients
Grant Year: 2020
Circulating low-density granulocytes (LDGs) are a subgroup of neutrophils with immunoregulatory functions which can spontaneously release extracellular web-like structures (NETs) and cytokines sustaining
T cell
T cell:
see lymphocyte
responses and dendritic cell activation. We hypothesize that LDGs and NETs might be impaired in functions and frequency during
myelodysplastic syndromes
myelodysplastic syndromes:
(my-eh-lo-diss-PLASS-tik SIN-dromez) A group of disorders where the bone marrow does not work well, and the bone marrow cells fail to make enough healthy blood…
Myelodysplastic syndrome (MDS) is a pre-cancerous disease of the blood, which progresses to the more aggressive
acute myeloid leukemia
acute myeloid leukemia:
(uh-KYOOT my-uh-LOYD loo-KEE-mee-uh) A cancer of the blood cells. It happens when very young white blood cells (blasts) in the bone marrow fail to mature. The blast cells stay in the bone marrow and become to numerous. This slows production of red blood cells and platelets. Some cases of MDS become…
(AML) in approximately 30% of cases. MDS currently affects about 60,000 people in the US, and about 10,000 new cases are…