Genomic context and TP53 allele frequency define clinical outcomes in TP53-mutated myelodysplastic syndromes
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Abstract TP53 mutations are associated with adverse outcomes and shorter response to hypomethylating agents (HMAs) in myelodysplastic syndrome (MDS). Limited data have evaluated the impact of the type, number, and patterns of TP53 mutations in response outcomes and prognosis of…
