Newsstand | Aplastic Anemia & MDS International Foundation

Here's where you'll find a regularly updated, broad range of articles written by the AAMDSIF team, allied health organizations and news organizations. By staying well-informed, patients and families are practicing a form of self-support that will help them be more effective self-advocates when engaging with health care providers.

Newsstand

Allogeneic Hematopoietic Cell Transplantation and Other Expensive Cellular Therapies: A Miracle for the Few but Off Limits to Many?

Originally Published: 11/15/2019
The number of patients undergoing allogeneic hematopoietic cell transplantation (HCT) for treatment of malignant and nonmalignant disorders has continued to grow worldwide. (footnotes) Great progress has been made in overcoming HLA/immunologic barriers, but nondonor barriers to HCT persist.(footnote) This represents a major unmet need because HCT is not accessible to everyone who would benefit from it.(footnote)

November 2019 AAMDSIF Update Newsletter

Originally Published: 11/14/2019

Summer 2019 MDS Update

Originally Published: 11/08/2019
Read the latest in what's happening in MDS research, hear from MDS patients and so much more! 

Genomic Biomarkers to Predict Resistance to Hypomethylating Agents in Patients With Myelodysplastic Syndromes Using Artificial Intelligence

Originally Published: 10/29/2019
We developed an unbiased framework to study the association of several mutations in predicting resistance to hypomethylating agents (HMAs) in patients with myelodysplastic syndromes (MDS), analogous to consumer and commercial recommender systems in which customers who bought products A and B are likely to buy C: patients who have a mutation in gene A and gene B are likely to respond or not respond to HMAs.

Dr. Babushok on Treatment Advances in Paroxysmal Nocturnal Hemoglobinuria

Originally Published: 10/24/2019
Daria V. Babushok, MD, PhD, an assistant professor of medicine, Perelman School of Medicine, University of Pennsylvania, discusses treatment advances in paroxysmal nocturnal hemoglobinuria (PNH).

When Your Child With a Rare Disease Doesn’t Feel Brave

Originally Published: 10/24/2019
Have you ever done something that you knew was the right thing to do, but you were scared to do it? Or maybe you did something that looked hard, but you decided to try it. That is courage in action and you probably felt very good about what you did. And you should! Courage shows up in many ways all around you. Courage is standing up for a friend, helping someone in need or sticking with something that is hard for you to do. They say that having courage makes you a better person, and courage is one of the most important faculties you can develop.   But what if being brave and courageous was...

October 2019 AAMDSIF Update Newsletter

Originally Published: 10/20/2019

Starting Chemotherapy, When You’re Ready

Originally Published: 10/17/2019
It’s better if you start cancer treatment when you can jump in wholeheartedly and without regrets. -by Mikkail Sekeres, MD in the New York Times    

When Mutant Cells Team Up, an Even Deadlier Blood Cancer Emerges [Video]

Originally Published: 10/14/2019
Sometimes the whole is greater than the sum of its parts. Researchers at Cold Spring Harbor Laboratory have discovered that two cell mutations, already harmful alone, enhance one another’s effects, contributing to the development of the deadly blood cancer acute myeloid leukemia (AML). CSHL Professor Adrian Krainer and his lab, along with Omar Abdel-Wahab at Memorial Sloan Kettering Cancer Center, detailed how mutations of the genes IDH2 and SRSF2 are unexpected partners-in-crime for causing AML.

September 2019 AAMDSIF Update Newsletter

Originally Published: 09/19/2019