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pediatric patient / parent

Sensitivity of Pediatric Myelodysplastic Syndromes With Excess of Blasts With UBTF–TD to Venetoclax/Azacitidine

UBTF-TD has been reported in a significant percentage of childhood MDS-EB and has been associated with inferior survival compared to that of patients with the wild-type gene. We treated three consecutive pediatric patients affected by UBTF-TD MDS-EB with venetoclax and azacitidine (ven/aza) in combination as 28-day cycles on a compassionate use basis three consecutive pediatric patients affected by UBTF-TD MDS-EB as a bridge to allogeneic HSCT. Treatment with ven/aza was well-tolerated, and all patients responded to the ven/aza course, achieving CR with flow-cytometry negativity.

Jeremy A. Meier, MD, PhD

Meier, Jeremy
Assistant Professor of Medicine
University of North Carolina at Chapel Hill School of Medicine

As a physician scientist Dr. Meier always had a passion for integrating patient care with research dedicated to improving cancer treatments. Clinically He is specialized in the management of patients with hematologic malignancies who are undergoing stem cell transplantation or receiving other cellular therapies, like CAR T cells. Dr. Meier research is focused on better understanding how to fully engage the immune system in its fight against cancer.

Halloween Benefit Bash

Hello Friends, Family, and our AAMDSIF Family!

We are excited to announce our upcoming Halloween Benefit Bash, where we aim to celebrate life and raise funds for the AA&MDS International Foundation—an organization that has provided incredible support to my family and many others throughout our journeys.

Tickets for this event are $50 each, and while we welcome any additional donations, your presence at the event would mean the world to us. If you're unable to attend but would like to contribute, we would greatly appreciate your support.

Event Date: 
Sat, 10/04/2025 - 5:00pm (EDT)
Bone Marrow Disease(s): 
Community Event Type: