pediatric patient / parent

Germline and somatic genetic landscape of pediatric myelodysplastic syndromes

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Abstract Pediatric myelodysplastic syndromes (MDS) represent a rare group of clonal hematopoietic stem cell disorders accounting for approximately 5% of pediatric hematologic malignancies. They are characterized by ineffective hematopoiesis, cytopenia, and dysplastic changes in…

Jeremy A. Meier, MD, PhD

Institution
University of North Carolina at Chapel Hill School of Medicine
About
As a physician scientist Dr. Meier always had a passion for integrating patient care with research dedicated to improving cancer treatments. Clinically He is specialized in the management of patients with hematologic malignancies who are undergoing stem cell transplantation or receiving other cellular therapies, like CAR T cells. Dr. Meier research is focused on better understanding how to fully engage the immune system in its fight against cancer. He is studying how extracellular signals in the tumor microenvironment regulate the function of immune cells with a particular interest in

Brandi Reeves, MD

Institution
University of North Carolina at Chapel Hill School of Medicine
Physician Status
accepting new patients
Primary Disease Area of Focus
Aplastic Anemia
Myelodysplastic Syndromes (MDS)
Myeloproliferative Neoplasms (MPN)
Paroxysmal Nocturnal Hemoglobinuria (PNH)
About
I am a physician-scientist specializing in myeloproliferative neoplasms (MPN), bone marrow failure syndromes, lower risk myelodysplastic syndromes (MDS), and clonal hematopoiesis. I lead our MPN program, which was established in 2019 and provides clinical and research expertise for MPN patients. My research primarily focuses on mechanisms of thrombosis in MPN, with a goal to improve MPN care by individualizing thrombosis risk stratification and by finding better treatments to prevent thrombosis. I am also dedicated to training the next generation of physicians and am involved in medical

Jose C. Martinez, MD, PhD

Institution
University of North Carolina at Chapel Hill School of Medicine
Physician Status
accepting new patients
Primary Disease Area of Focus
Acute Myeloid Leukemia (AML)
Aplastic Anemia
Myelodysplastic Syndromes (MDS)
Myeloproliferative Neoplasms (MPN)
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Pediatric
About
I am a physician-scientist who sees patients in clinic with disorders of clonal hematopoiesis and myeloid cancers, including acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). My clinical and research interests focus on RNA regulation in hematologic malignancies. Specifically, I investigate how mutations in splicing factors affect RNA processing and contribute to disease progression. These genetic mutations can occur at any stage of life, leading to complex disorders that are often challenging to diagnose and treat. In the laboratory, we utilize advanced genomic technologies

Inherited Bone Marrow Failure - Pediatric Patients - 2025 San Francisco Bay Area Patient and Family Conference

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Topic(s)
Pediatric Bone Marrow Failure Diseases
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Aplastic Anemia
Myelodysplastic Syndromes (MDS)
Presenter(s)
Jessie Alexander, MD
Rajni Agarwal, MD
Which bone marrow failure diseases can be inherited? Why? How? Find the answers to these questions and more in this recording from the 2025 San Francisco Bay Area Patient and Family Conference.

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