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paroxysmal nocturnal hemoglobinuria (PNH)

Frequency and perturbations of various peripheral blood cell populations before and after eculizumab treatment in paroxysmal nocturnal hemoglobinuria

Author(s): 
Carmelo Gurnari, Amy C Graham, Alexey Efanov, Simona Pagliuca, Jibran Durrani, Hassan Awada, Bhumika J Patel, Alan E Lichtin, Valeria Visconte, Mikkael A Sekeres, Jaroslaw P Maciejewski
Primary Author: 
Gurnari C
Journal Title: 
Blood cells, molecules and diseases
Original Publication Date: 
Mar 2021

While red blood cells (RBCs) and granulocytes have been more studied, platelets and reticulocytes are not commonly used in

Implication of PIGA genotype on erythrocytes phenotype in Paroxysmal Nocturnal Hemoglobinuria

Author(s): 
Gurnari C, Pagliuca S, Patel BJ, Awada H, Kongkiatkamon S, Terkawi L, Zawit M, Corey S, Lichtin AE, Carraway HE, Wahida A, Visconte V, Maciejewski JP
Primary Author: 
Gurnari C
Journal Title: 
Leukemia
Original Publication Date: 
Jan 2021

James Cook, MD, PhD

MD, PhD Cook, James
Professor of Pathology
Cleveland Clinic, Learner School of Medicine

James R. Cook, M.D., Ph.D., is a Professor of Pathology at the Cleveland Clinic Lerner College of Medicine.  He serves as Section Head of Hematopathology in the Department of Laboratory Medicine.  Dr. Cook's clinical interests focus on diagnostic hematopathology and molecular diagnostics.

We Made It! – Kristy Shares her Perspective in January 2021

Person's Name: 
Kristy Maliczowski

We made it to another treatment day without anyone in our family getting sick! The week leading to treatment day has become pretty worrisome for me. What if someone in our family gets sick with or is exposed to COVID? Josh will not be able to get his infusion within the treatment window and then what? The questions I never thought I'd have to wonder about. I used to dread treatment day because it was a reminder that Josh has

Content source: 

Is blood transfusion safe during the COVID-19 pandemic?

Author(s): 
Josiane Bassil, Elie Rassy, Joseph Kattan
Primary Author: 
Bassil J
Journal Title: 
Future Science OA
Original Publication Date: 
Sep 2020

The rapid spread of the coronavirus disease 2019 (COVID-19) pandemic has challenged healthcare systems to re-organize the management of patients in a short period. The causative pathogen of this pandemic is severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), one of seven coronaviruses that can be found in humans. It is a rapidly mutating, enveloped, ssRNA, beta-coronavirus. The initial reports published after the pandemic spread showed a transmissibility rate of 2.2 and possibly low values of dispersion.

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