paroxysmal nocturnal hemoglobinuria (PNH) | Aplastic Anemia & MDS International Foundation

paroxysmal nocturnal hemoglobinuria (PNH)

Ramy M. Hanna, MD, FASN, FACP

Hanna, Ramy
Assistant Clinical Professor of Medicine and Nephrology
University of California Irvine

Dr. Ramy Hanna is an Assistant Clinical Professor of Medicine and Nephrology at the University of California Irvine UCI-Health.  He is a clinician-educator who works at the intersection of patient education and research, participating in ongoing research into diseases of the kidneys (nephrology) as it relates to complement disorders such as PNH.  Dr. Hanna is focused on working with underserved communities and the expanding field of Artificial Intelligence/Machine Learned related to improving the diagnostic process and treatment outcomes for patients. 

Patients with paroxysmal nocturnal hemoglobinuria demonstrate a prothrombotic clotting phenotype which is improved by complement inhibition with eculizumab

Author(s): 
Macrae FL, Peacock-Young B, Bowman P, Baker SR, Quested S, Linton E, Hillmen P, Griffin M, Munir T, Payne D, McKinley C, Clarke D, Newton DJ, Hill A, Ariëns RAS
Primary Author: 
Macrae FL
Journal Title: 
American Journal of Hematology
Original Publication Date: 
Aug 2020

Robert Collins, MD

Collins, Robert
Director of both the Hematologic Malignancies/Blood and Marrow Transplantation Program and the Combined Adult/Pediatric Stem Cell Transplant Program
Harold C. Simmons Comprehensive Cancer Center

A recognized leader in the field of adoptive immunotherapy, Dr. Collins specializes in blood and marrow transplantation and hematologic malignancies such as leukemia, lymphoma, myeloma, Hodgkin’s disease, and myelodysplasia.

Dr. Collins earned his medical degree from the University of Missouri-Kansas City School of Medicine. He completed an internal medicine residency at Baylor University Medical Center in Dallas, as well as a fellowship in hematology and oncology at the University of California at Los Angeles.

Vijaya Bhatt, MD

Bhatt, Vijaya
Associate Professor
University of Nebraska Medical Center

Dr. Vijaya Raj Bhatt graduated from Institute of Medicine, Tribhuvan University in Nepal in 2009 with a degree of Bachelor of Medicine and Bachelor of Surgery (MBBS). He then went on to do a three-year residency in internal medicine in Staten Island University Hospital in Staten Island, New York. During his residency, he was awarded the resident of the year for three consecutive years. After completing his residency, he joined the University of Nebraska Medical Center in Nebraska and completed his fellowship in hematology-oncology.

Pinkal Desai, MD, MPH

Desai, Pinkal
Assistant Professor of Medicine
New York Presbyterian Hospital/Weill Cornell Medicine

After obtaining her MBBS at Byramjeejeebhoy Medical College in India in 2005, Dr. Desai obtained an MPH at the University of Alabama at Birmingham School of Public Health.  Following her residency at Wayne State University, Detroit Medical Center, she underwent fellowship training in Hematology-Medical Oncology at Providence Hospital Medical Center, serving as Chief Fellow from 2012-2013. Dr. Desai was recruited to serve in our Leukemia Program to develop a clinical practice devoted to leukemia, myelodysplastic syndrome (MDS) and myeloproliferative neoplasms (MPN).

Beneficial effects of eculizumab regardless of prior transfusions or bone marrow disease: Results of the International PNH Registry

Author(s): 
Alexander Röth, David J Araten, Loree Larratt, Austin G Kulasekararaj, Jaroslaw P Maciejewski, Amanda Wilson, Philippe Gustovic, Yuzuru Kanakura
Primary Author: 
Röth A
Journal Title: 
European Journal of Haematology
Original Publication Date: 
Jul 2020

Objectives: To evaluate the effects of

Thomas G. DeLoughery, MD, MACP, FAWM

DeLoughery, Thomas
Professor of Medicine
Oregon Health & Science University

Tom DeLoughery is a native Hoosier who graduated from Indiana State University in 1981 (one year after Larry Bird) and the Indiana University School of Medicine in 1985. He did his internship at the University of California, Irvine before traveling to Oregon where he finished his internal medicine residency and hematology/oncology fellowship.