Weina Chen, MD, PhD

Dr. Weina Chen is the Medical Director of Hematopathology Division at The University of Texas Southwestern Medical Center (UTSWMC). She received her medical degrees at Shanghai Medical College of Fudan University, China, and PhD degree in Biophysics at Ecole Polytechnique, France. After four years of basic research basic research: The study of a subject to increase knowledge and understanding about it. The goal of basic research in medicine is to better understand disease. In the laboratory, basic research scientists study changes in cells and molecules linked to disease. Basic research helps lead to better ways of… in ischemic heart conditioning at Duke University and National Institute of Environmental Health Sciences (NIEHS), she went to UTSWMC where she completed her Pathology residency and Hematopathology fellowship. Dr. Chen served as faculty at MD Anderson Cancer Center and moved back to UTSWMC where she reached the rank of professor.

Dr. Chen’s clinical focus is on the diagnosis of hematolymphoid malignancies including leukemia and lymphoma by morphology morphology: The study of the structure and form of an organism or one of its parts. and flow cytometry flow cytometry: (sy-TOM-uh-tree) A laboratory test that gives information about cells, such as size, shape, and percentage of live cells. Flow cytometry is the test doctors use to see if there are any proteins missing from the surface of blood cells. It is the standard test for confirming a diagnosis of paroxysmal… in conjunction with genetic studies. Most of her research studies have come from the observations that she has made at the microscope and flow cytometry. The intriguing findings of disease patterns under the microscope and various cell populations by flow cytometry sparked her intellectual curiosity to explore the underling molecular pathogenesis. The findings from these studies have not only advanced our understanding of the biology of these diseases but also enhanced the diagnostic powers, including the recommendation in our clinical practice. Notable contribution included copper testing in cytopenia cytopenia: (sie-tuh-PEE-nee-uh) A shortage of one or more blood cell types. Also called a low blood count. work-up, flow cytometric biomarkers for myelodysplastic syndromes myelodysplastic syndromes: (my-eh-lo-diss-PLASS-tik SIN-dromez) A group of disorders where the bone marrow does not work well, and the bone marrow cells fail to make enough healthy blood cells. Myelo refers to the bone marrow. Dysplastic means abnormal growth or development. People with MDS have low blood cell count for at… and MYC rearranged aggressive lymphomas, and novel biomarkers (e.g. LILRB1 and LILRB4) for acute monocytic leukemia.

Dr. Chen has authored more than 100 peer-reviewed articles and book chapters including 5th WHO classifications of Tumours. She has served as an editorial board member of Seminars in Diagnostic Pathology, a member of International Clinical Flow Cytometry Education Committee, College of American Pathology (CAP)/Hematolymphoid Cancer Protocol Protocol: An action plan that describes what will be done in a clinical trial and how it will be carried out. This plan is reviewed and approved by a committee at each place doing the clinical trial. This committee is known as the Institutional Review Board. Review Committee, and National Comprehensive Cancer Network (NCCN) Guideline Committee on Hodgkin lymphoma.