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Research Articles

Compiled for your convenience are articles on bone marrow failure research and treatment from the world’s major journals on hematology / oncology.

Article Title Original Publication Date Journal Bone Marrow Disease
To Target the Untargetable: Elucidation of Synergy of APR-246 and Azacitidine in TP53 Mutant Myelodysplastic Syndromes and Acute Myeloid Leukemia Jun 2020 Haematologica Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS)
Time without transfusion reliance: a novel patient-centric metric for new therapies in myelodysplastic syndromes Apr 2023 Haematologica Myelodysplastic Syndromes (MDS)
Current use of androgens in bone marrow failure disorders: a report from the Severe Aplastic Anemia Working Party of the European Society of Blood and Marrow Transplantation May 2023 Haematologica Aplastic Anemia
Immunosuppressive therapy for pediatric aplastic anemia: a North American Pediatric Aplastic Anemia Consortium study Apr 2019 Haematologica Aplastic Anemia
Characterization of breakthrough hemolysis events observed in the phase 3 randomized studies of ravulizumab versus eculizumab in adults with paroxysmal nocturnal hemoglobinuria Jan 2020 Haematologica Paroxysmal Nocturnal Hemoglobinuria (PNH)
Phase II trials of zilucoplan in paroxysmal nocturnal hemoglobinuria Aug 2023 Haematologica Paroxysmal Nocturnal Hemoglobinuria (PNH)
Danicopan: an oral complement factor D inhibitor for paroxysmal nocturnal hemoglobinuria Oct 2020 Haematologica Paroxysmal Nocturnal Hemoglobinuria (PNH)
Predicting response of severe aplastic anemia to immunosuppression combined with eltrombopag Apr 2021 Haematologica Aplastic Anemia
Diagnosis of myelodysplastic syndromes: the classic and the novel Oct 2024 Haematologica Myelodysplastic Syndromes (MDS)
Antithymocyte globulin and cyclosporin: standard of care also for older patients with aplastic anemia. Feb 2019 Haematologica Aplastic Anemia