Yeung Chul Mun, MD
Mun, Yeung Chul
Professor
Ewha Woman's Medical Center Seoul Hospital
treatment
Tamara K. Moyo, MD
Moyo, Tamara
Assistant Professor of Medicine
Atrium health
Online Profile:
Catherine E. McGuinn, MD
McGuinn, Catherine
Assistant Professor of Medicine
Weill Cornell Medicine
Online Profile:
Adriana K Malone, MD
Malone, Adriana
Associate Professor
Icahn School of Medicine at Mount Sinai
Online Profile:
Leo Luznik, MD
Luznik, Leo
Associate Professor
Johns Hopkins University
Online Profile:
Sydney X. Lu, MD
Lu, Sydney
Assistant Professor of Medicine
Stanford University School of Medicine
Online Profile:
Thomas P. Loughran Jr, MD
Loughran, Thomas
Director, UVA Cancer Center
UVA Cancer Center
Online Profile:
Bradley H. Lewis, MD
Lewis, Bradley
Hematologist/Oncologist
Permanente Medical Group Inc
Eltrombopag in combination with immunosuppressive therapy in pediatric severe aplastic anemia: Phase 2 ESCALATE trial
Key Points
Eltrombopag combined with IST demonstrated a trend towards a favorable ORR in pediatric patients with r/r SAA.
The PK profile for eltrombopag was similar to that observed in patients with ITP, and no unexpected safety signals were observed in children
Donor regulatory T-cell therapy to prevent graft-versus-host disease
Key Points
Treg-engineered donor graft prevents acute and chronic GVHD.
Patients treated with Treg-engineered graft who develop GVHD respond to primary corticosteroid therapy at a high rate.