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AAMDSIF provides educational materials for patients and healthcare professionals written in plain language and reviewed by highly respected and recognized medical doctors who are experts in bone marrow failure
Myelodysplastic Syndromes (MDS)
Study Connects Agent Orange Exposure to Earlier and More Severe Cases of Myelodysplastic Syndrome
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Summary Many veterans and doctors have long questioned whether Agent Orange (AO) exposure during the Vietnam War contributed to cases of myelodysplastic syndrome (MDS), a type of blood cancer. The contaminated chemical is linked to several cancers, but a link to MDS was unclear…
Inflammatory stromal and T cells mediate human bone marrow niche remodeling in clonal hematopoiesis and myelodysplasia
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Abstract Somatic mutations in hematopoietic stem/progenitor cells (HSPCs) can lead to clonal hematopoiesis of indeterminate potential (CHIP) and progression to myelodysplastic syndromes (MDS). Using single-cell and anatomical profiling of a large cohort of human bone marrow (BM)…
Rapid clonal selection within early hematopoietic cell compartments presages outcome to ivosidenib combination therapy
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Key Points Ivosidenib, venetoclax ± azacitidine either rapidly selects evolved, resistant leukemic clones or eradicates leukemic clones. Resistant clones express RNA signatures of stemness, branched-chain amino acid metabolism, and menin targets. Subjects:Myeloid Neoplasia…
Infections in lower-risk myelodysplastic syndromes - prevalence and risk factors: a report from the European MDS Registry
Infections are an important cause of morbidity and mortality in patients with lower-risk myelodysplastic syndromes myelodysplastic syndromes:
Optimal timing of allogeneic hematopoietic stem cell transplant in MDS
Myelodysplastic neoplasms (MDS) are clonal hematopoietic disorders characterized by ineffective hematopoiesis hematopoiesis: (hi-mat-uh-poy-EE-suss) The process of making blood cells in
Understanding Aplastic Anemia and Overlapping Diseases
Learn more about the connection between aplastic anemia and other bone marrow failure diseases.
Transplant Patient Card
Emergency health information card for patients who have received a transplant.
Non Transplant Patient Card
Emergency health information card for patients who have not received a transplant.
Instructions
Not all healthcare professionals or emergency responders will understand your rare diagnosis and unique needs. AAMDSIF has created an emergency health information card that communicates to others what they need to know…