ESCALATing care? Eltrombopag in pediatric aplastic anemia
In this issue of Blood Advances, Shimamura et al1 report on a phase 2 clinical trial clinical trial: A type of research study that tests how a drug, medical device, or treatment app
Aplastic Anemia
The landscape of disease: mapping aplastic anemia
The development of antibody-based spatial multiplex assays, and the more recent introduction of spatial transcriptomic and proteomic platforms, now allows the characterization and profiling of human tissue samples at unprecedented depth, opening up a new exciting window for a better understanding of human pathology in situ, in both inflammatory and neoplastic conditions.
Understanding Brain Fog, Chemo Brain, with Dr. Jorg Dietrich
Topic(s)
Living Well with Bone Marrow Failure
Managing Your Treatment
Presenter(s)
Jorg Dietrich, MD, PhD
In this webinar, Dr. Jorg Dietrich will discusses the diagnosis of brain fog/chemo brain and how patients can manage this symptom of disease and its treatments.
Advances in Transplant and GVHD with Dr. Corey Cutler
Topic(s)
Bone Marrow Transplant
Presenter(s)
Corey Cutler, MD, MPH, FRCPC
In this webinar, Dr. Corey Cutler discusses advances in transplant and treating GVHD, or Graft Versus Host Disease.
Hematopoietic stem cell transplantation is effective in achieving long-term survival for post-aplastic anemia myeloid neoplasms: the EBMT Severe Aplastic Anemia Report
Original Publication Date
Article Source
External Web Content
Abstract Aplastic anemia (AA) transformation into myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML) is associated with a dismal prognosis. Hematopoietic stem cell transplant offers the sole possibility of cure, but data on long-term survival are scarce. We…
Active Middle-Schooler's Life Sidelined by Severe Aplastic Anemia - Phoenix's Story
Cheer, music, sports, plays, community. These dominated Phoenix’s life in the autumn of last year.
Transplant and GVHD: Aplastic Anemia and PNH - 2025 San Francisco Bay Area Conference
Topic(s)
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Bone Marrow Transplant
Aplastic Anemia
Presenter(s)
Judith Shizuru, MD
Dr. Judith Shizuru explains how Transplantation can be used to treat Aplastic Anemia and PNH. She discusses how GVHD, or Graft VS Host Disease, can occur after transplant as well.
23-Year Aplastic Anemia Survivor Speaks - 2025 San Francisco Bay Area Patient/Family Conference
Topic(s)
Aplastic Anemia
What do you go through to treat of Aplastic Anemia? What is life like afterwards? What kind of life can you lead? Kinsey describes her journey in this recording from the 2025 San Francisco Bay Area Patient and Family Conference.
Clinical Trial Clinical Trial: A type of research study that tests how a drug, medical device, or treatment approach works in people. There are several types of clinical trials. Treatment trials test new treatment options. Diagnostic trials test new ways to diagnose a disease. Screening trials test the best way to detect a disease or health problem. Quality of life (supportive care) trials study ways to improve the comfort of people with chronic illness. Prevention trials look for better ways to prevent disease in people who have never had the disease. Trials are in four phases. Phase I tests a new drug or treatment in a small group to see if it is safe. Phase II expands the study to a larger group of people to find out if it works. Phase III expands the study to an even larger group of people to compare it to the standard treatment for the disease; and Phase IV takes place after the drug or treatment has been licensed and marketed to find out the long-term impact of the new treatment. CureAA: Clinical Trial of Upfront Haploidentical or Unrelated Donor BMT to Restore Normal Hematopoiesis in Aplastic Anemia
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Status
Recruiting
Study Date (Range)
-
Bone Marrow Disease(s)
Aplastic Anemia
Age Group
3 years to 75 years
This is a Phase II study of hematopoietic stem cell transplantation for previously untreated patients with severe aplastic anemia. This study is comprised of two cohorts - patients receiving haploidentical donor transplant and patients receiving unrelated donor transplant. The…
Treatment patterns and blood count control in 10,112 patients with polycythemia vera
Original Publication Date
Article Source
External Web Content
ABSTRACT Background Elevated blood counts in polycythemia vera (PV) are associated with increased thrombotic risk, which contributes to morbidity and mortality. Research design and methods This retrospective study describes treatment patterns and blood count control in patients…