- paroxysmal nocturnal hemoglobinuria (PNH)
Ravulizumab-cwvz (Ultomiris®) is a drug approved by the U.S. Food and Drug Administration (FDA) in 2018 to treat PNH. ULTOMIRIS® is a long-acting C5 inhibitor that works by inhibiting the C5 protein in the terminal complement cascade.
ULTOMIRIS® is a prescription medicine called a monoclonal antibody. ULTOMIRIS® is used to treat adults with a disease called Paroxysmal Nocturnal Hemoglobinuria (PNH). It is not known if ULTOMIRIS® is safe and effective in children. ULTOMIRIS® is a long-acting C5 inhibitor administered every eight weeks that works by inhibiting the C5 protein in the terminal complement cascade.
ULTOMIRIS® increases your chance of getting serious and life-threatening meningococcal infections. Meningococcal infections may quickly become life-threatening and cause death if not recognized and treated early.
For more information, please see the therapy page about this drug.