What is PNH?
Basic description of PNH and how it affects your bone marrow and blood
diagnosis
Order Patient Educational Materials
AAMDSIF provides educational materials for patients and healthcare professionals written in plain language and reviewed by highly respected and recognized medical doctors who are experts in bone marrow failure
Study Connects Agent Orange Exposure to Earlier and More Severe Cases of Myelodysplastic Syndrome
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Summary Many veterans and doctors have long questioned whether Agent Orange (AO) exposure during the Vietnam War contributed to cases of myelodysplastic syndrome (MDS), a type of blood cancer. The contaminated chemical is linked to several cancers, but a link to MDS was unclear…
Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia
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Highlights Heme biosynthesis enzymes are variably suppressed in AML Heme levels are linked with altered leukemic transcriptional programs via BACH1 Heme biosynthesis is a selective dependency in AML, both in vitro and in vivo Heme starvation disrupts complex IV, inducing copper…
Inflammatory stromal and T cells mediate human bone marrow niche remodeling in clonal hematopoiesis and myelodysplasia
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Abstract Somatic mutations in hematopoietic stem/progenitor cells (HSPCs) can lead to clonal hematopoiesis of indeterminate potential (CHIP) and progression to myelodysplastic syndromes (MDS). Using single-cell and anatomical profiling of a large cohort of human bone marrow (BM)…
Understanding PNH Treatment Options
Summary of FDA-approved medicines for treating PNH and transplantation options.
Platelet Transfusion Record
Form to keep track of platelet transfusions as part of aplastic anemia treatment.
My Healthcare Team
Chart to record medical professionals, pharmacy contacts, patient support organizations and others involved with your health care.
Find an Aplastic Anemia Specialist
Use the AAMDS Map of Specialists to find an Aplastic Anemia expert.
Preparing for Medical Visits
Guidelines and suggested questions for making the most of your health care appointments.