Myelodysplastic Syndromes (MDS)
Guillermo Montalban Bravo, MD
Lisa McReynolds, MD,PhD
Lisa J. McReynolds, M.D., Ph.D., joined the Clinical Genetics Branch (CGB) as a clinical fellow in 2016, was promoted to assistant clinical investigator in 2019 and became a Lasker Clinical Research Scholar in 2024. She earned her M.D. and Ph.D. at Albert Einstein College of Medicine, where she studied Smad signaling in a zebrafish model of hematopoiesis in the laboratory of Todd Evans, Ph.D. (2009). Dr. McReynolds then completed a residency in pediatrics at Morgan Stanley’s Children’s Hospital of New York-Presbyterian Hospital and fellowship through the joint program of Johns Hopkins
Enrico Attardi, MD, PhD
MD, PhD. My main scientific interests concern germline predisposition to bone marrow failures and myeloid neoplasms, particularly to myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). I am also deeply intrigued by the intersection of inborn errors of immunity (IEIs) and hemopathies.
Matteo Della Porta, MD
Matteo Giovanni Della Porta is head of Leukemia Unit at Humanitas Cancer Center in Milan, where he is also the head of the Genomics of Hematological Neoplasms Lab. He is full professor of Hematology at Humanitas University and director of the Center for Acclelerating Leukemia/Lymphoma Research, a joint effort from Humanitas University, Humanitas Research Hospital, Humanitas AI Center and the Politecnico di Milano. He obtained his Medical Degree with honors at the University of Pavia Medical School, Italy in 1999. From 2000 to 2003 he completed his training in Hematology at the Department of
How I select hematopoietic cell donors in the era of posttransplant cyclophosphamide
Abstract Selection of a hematopoietic progenitor cell donor for allogeneic hematopoietic cell transplantation (HCT) is essential for treatment planning; however, the parameters that define an “optimal” donor in the modern era are not well defined. Historically, donor-recipient…
Impact of allogeneic stem cell transplantation in patients with higher risk myelodysplastic syndromes
Abstract Allogeneic stem cell transplantation (SCT) is a curative treatment in myelodysplastic syndromes (MDS). We performed a retrospective single center study of all patients with newly diagnosed higher risk (HR) MDS (IPSS-R > 3.5 points) between 2000 and 2023. We identified…
Expert Opinion on the Diagnosis and Treatment of Hematologic Malignancies During Pregnancy
Abstract The diagnosis and treatment of hematologic malignancies has undergone significant advancements over the past few decades, resulting in enhanced outcomes. For hematologic malignancies diagnosed during pregnancy, this poses new questions. As possibilities continue to…
Treatment of TP53-mutated myelodysplastic syndrome and acute myeloid leukemia with lowintensity metronomic decitabine and venetoclax
Abstract Venetoclax (Ven) in combination with hypomethylating agents (HMA) (azacitidine or decitabine) is the standard of care for elderly or unfit patients with acute myeloid leukemia (AML) and is being explored in high-risk myelodysplastic syndrome (HR-MDS). However, currently…