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aplastic anemia

Multicenter evaluation of the addition of eltrombopag to immunosuppressive therapy for adults with severe aplastic anemia

Author(s): 
Shinn LT, Benitez LL, Perissinotti AJ, Reid JH, Buhlinger KM, van Deventer H, Barth D, Wagner CB, Zacholski K, Desai R, Soule A, Stump SE, Weis TM, Bixby D, Burke P, Pettit K, Marini BL
Primary Author: 
Shinn LT
Journal Title: 
International Journal of Hematology
Original Publication Date: 
Oct 2023

Clonal Hematopoiesis, Inflammation, and Hematologic Malignancy

Author(s): 
Kanagal-Shamanna R, Beck DB, Calvo KR
Primary Author: 
Kanagal-Shamanna R
Journal Title: 
Annual Review of Pathology: Mechanisms of Disease
Original Publication Date: 
Oct 2023

Somatic or acquired mutations are postzygotic genetic variations that can occur within any tissue. These mutations accumulate during aging and have classically been linked to malignant processes. Tremendous advancements over the past years have led to a deeper understanding of the role of somatic mutations in benign and malignant age-related diseases. Here, we review the somatic mutations that accumulate in the blood and their connection to disease states, with a particular focus on inflammatory diseases and myelodysplastic syndrome.

Bone Marrow Disease(s): 

Deciphering treatment patterns in non-severe/moderate aplastic anemia: an international observational study

Author(s): 
Fattizzo B, Gurnari C, Cassanello G, Bortolotti M, Awada H, Giammarco S, Consonni D, Sica S, Gandhi S, Trikha R, Large J, Salter S, Maciejewski JP, Barcellini W, Kulasekararaj AG
Primary Author: 
Fattizzo B
Journal Title: 
Leukemia
Original Publication Date: 
Oct 2023

Non-severe

Bone Marrow Disease(s): 

Aplastic Anemia, MDS, and PNH Virtual Support Group -Saturdays- 2023 December

Event Date: 
Sat, 12/16/2023 - 10:30am (EST)

AAMDSIF is pleased to announce that we will host a support group for patients diagnosed with

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