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aplastic anemia

Alternative donor BMT with post-transplant cyclophosphamide as initial therapy for acquired severe aplastic anemia

Author(s): 
DeZern A, Zahurak ML, Symons HJ, Cooke KR, Huff CA, Jain T, Swinnen LJ, Imus PH, Wagner-Johnston ND, Ambinder RF, Levis MJ, Luznik L, Bolaños-Meade J, Fuchs EJ, Jones RJ, Brodsky RA
Primary Author: 
DeZern A
Journal Title: 
Blood
Original Publication Date: 
Apr 2023

Severe

Bone Marrow Disease(s): 

What causes aplastic anaemia?

Author(s): 
Gale RP, Hinterberger W, Young NS, Gennery AR, Dvorak CC, Hebert KM, Heim M, Broglie L, Eapen M
Primary Author: 
Gale RP
Journal Title: 
Leukemia
Original Publication Date: 
Apr 2023

Aplastic anaemia has diverse aetiologies including: (1) direct damage to haematopoietic stem or progenitor cells such as from chemicals, drugs and ionising radiations; (2) an abnormal bone marrow micro-environment, (3) immune-mediated mechanism(s); or (4) combination of these.

Bone Marrow Disease(s): 
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