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Emerging Therapeutics for the Control of Chronic Graft-versus-Host Disease

Author(s): 
MacDonald, K. P. A., Betts, Brian C, Couriel, D.
Primary Author: 
MacDonald, K. P. A.
Journal Title: 
Biology of Blood and Marrow Transportation
Original Publication Date: 
Jan 2018

Chronic graft-versus-host disease (cGVHD) currently represents the leading cause of nonrelapse mortality and morbidity after allogeneic hematopoietic stem cell transplantation (SCT). In parallel with an increased use of

Bone Marrow Diseases: 

Welcome to our blog!

Greetings and welcome to #MarrowStrong blog!

We’ll be posting a new blog twice a month on the best information for patients and families, and we hope to bring a smile, too!.

We  have a lot of events lined up for 2018, planned for you and the #MarrowStrong community:

Cover Photo: 

Rational Management Approach To Pure Red Cell Aplasia

Author(s): 
Suresh Kumar Balasubramanian, Meena Sadaps, Swapna Thota, Mai Aly, Bartlomiej P. Przychodzen, Cassandra M. Hirsch, Valeria Visconte, Tomas Radivoyevitch, Jaroslaw P. Maciejewski
Primary Author: 
Maciejewski J
Journal Title: 
Haematologica
Original Publication Date: 
Dec 2017

Pure red cell aplasia is an orphan disease without rationally established standard therapies. Most cases are idiopathic; a subset is antibody-mediated. There is overlap between idiopathic cases and those with T-large granular lymphocytic leukemia, hypogammaglobulinemia, and low-grade lymphomas. In all these, the pathogenetic mechanisms may involve autoreactive cytotoxic responses.

Bone Marrow Diseases: 

Genetic Mutations for AML found Years before Diagnosis

 Patients with acute myeloid leukemia (AML) may have genetic mutations in their blood indicating they are at high risk of developing the disease about nine years before diagnosis, according to research from Weill Cornell Medicine and NewYork-Presbyterian investigators. They presented their findings at the 59th annual American Society of Hematology meeting on Dec. 10 in Atlanta, Ga. Full article here