| Page 17 | Aplastic Anemia and MDS International Foundation

Management of thrombosis in paroxysmal nocturnal hemoglobinuria: a clinician's guide

Author(s): 
Griffin M, Munir T
Primary Author: 
Griffin M
Journal Title: 
Ther Adv Hematol
Original Publication Date: 
Mar 2017

Paroxysmal nocturnal haemoglobinuria (PNH), an ultra-orphan disease with a prevalence of 15.9 per million in Europe, is a life-threatening disorder, characterized by haemolysis,

Relation between chelation and clinical outcomes in lower-risk patients with myelodysplastic syndromes: Registry analysis at 5 years

Author(s): 
Lyons RM, Marek BJ, Paley C, Esposito J, McNamara K, Richards PD, DiBella N, Garcia-Manero G.
Primary Author: 
Lyons RM
Journal Title: 
Leuk Res
Original Publication Date: 
Jan 2017

Prospective data are needed to ascertain the impact of

Bone Marrow Diseases: 

Cardiac iron overload in chronically transfused patients with thalassemia, sickle cell anemia, or myelodysplastic syndrome

Author(s): 
de Montalembert M, Ribeil JA, Brousse V, Guerci-Bresler A, Stamatoullas A, Vannier JP, Dumesnil C, Lahary A, Touati M, Bouabdallah K, Cavazzana M, Chauzit E, Baptiste A, Lefebvre T, Puy H, Elie C, Karim Z, Ernst O, Rose C
Primary Author: 
de Montalembert M
Journal Title: 
PLoS One
Original Publication Date: 
Mar 2017

The risk and clinical significance of cardiac

Bone Marrow Diseases: 

Focal Adhesion Kinase as a Potential Target in AML and MDS

Author(s): 
Carter BZ, Mak PY, Wang X, Yang H, Garcia-Manero G, Mak D, Mu H, Ruvolo V, Qiu Y, Coombes K, Zhang N, Ragon B, Weaver DT, Pachter JA, Kornblau S, Andreeff M
Primary Author: 
Carter BZ
Journal Title: 
Mol Cancer Ther
Original Publication Date: 
Mar 2017

Although overexpression/activation of focal adhesion kinase (FAK) is widely known in solid tumors to control cell growth, survival, invasion, metastasis, gene expression, and stem cell self-renewal, its expression and function in myeloid leukemia are not well investigated.

Bone Marrow Diseases: 

Self-reported sleep disturbance and survival in myelodysplastic syndromes

Author(s): 
Luskin MR, Cronin AM, Owens RL, DeAngelo DJ, Stone RM, Wadleigh M, Steensma DP, Abel GA
Primary Author: 
Luskin MR
Journal Title: 
Br J Haematol
Original Publication Date: 
Mar 2017

Neither the prevalence of sleep disturbance nor its association with fatigue and overall survival (OS) are well understood for patients with

Bone Marrow Diseases: