Recent Research Information on Aplastic Anemia, MDS, and PNH

AA&MDSIF strives to keep patients, families, and hematology/oncology professionals up-to-date with developments in research and practice relevant to aplastic anemia, MDS and PNH. Shown below are recent articles from major hematology/oncology journals, retrieved from the National Library of Medicine’s PubMed portal to their MEDLINE database of journal citations and abstracts of the biomedical literature from around the world.


Looking for research oriented for patients and caregivers? For select reviews of important medical journal articles, written by hematology/oncology professionals, visit Research Reviews for Patients. These reviews interpret the most relevant information for patients from the latest published research.

Summary information is listed by publication date, title, journal title and senior author. By default, the articles are listed by their publication date in reverse chronological order, from the most recent article to oldest article. Clicking the date column heading will sort them the other way, from oldest to newest.

"Publication date" in most cases means when the article first appeared in the electronic/online issue of a journal, in advance of when it appears in the print journal. Keep in mind some articles may appear online months before appearing in print, and that some may be from online-only journals.

You can also alphabetically and reverse alphabetically sort articles, primary authors and journal titles by clicking their column heading. To find articles by disease type, choose it from the drop-down menu named "Filter by Disease", and only articles about those diseases will appear. The search box labeled “Filter by Search Term” lets you search for a word in the article title, author, or journal name.

When you open an article citation by clicking on the title, article summary information (this time including all authors) is again shown, and in most cases you can view the article abstract. In some cases the abstract is unavailable, and not shown. You can also progress to the article’s PubMed entry by clicking the PubMed ID number link, shown directly under the title. Here you can purchase the article for download viewing or view through your institutional library’s access. In some cases, full text viewing is free either from the publisher’s site or from PubMed Central, an searchable aggregation site of free full text articles.

The PubMed Web site has extensive features, along with help tools and links to other databases. Regular users are encouraged to become familiar with its many capabilities.

Publication Date Article Title Journal Title Primary Author Bone Marrow Disease(s)
04/27/2013 5-Azacytidine for the treatment of myelodysplastic syndromes. Expert Opin Pharmacother Krawczyk J myelodysplastic syndromes (MDS)
04/25/2013 Response to lenalidomide in myelodysplastic syndromes with del(5q): influence of cytogenetics and mutations. Br J Haematol Mallo M myelodysplastic syndromes (MDS)
04/22/2013 Thrombosis in paroxysmal nocturnal hemoglobinuria. Blood Hill A paroxysmal nocturnal hemoglobinuria (PNH)
04/20/2013 Validation of the revised international prognostic scoring system in treated patients with myelodysplastic syndromes. Am J Hematol Mishra A myelodysplastic syndromes (MDS)
04/14/2013 Less could be better: The case for reducing the dose of cyclophosphamide for children undergoing allogeneic stem cell transplant for severe aplastic anemia. Pediatr Transplant Hussein AA aplastic anemia
04/12/2013 A multivariate analysis of the relationship between response and survival among patients with higher-risk myelodysplastic syndromes treated within azacitidine or conventional care regimens in the randomized AZA-001 trial. Haematologica Gore SD myelodysplastic syndromes (MDS)
04/10/2013 How we treat lower risk myelodysplastic syndromes. Blood Fenaux P myelodysplastic syndromes (MDS)
04/03/2013 Reduced dose cyclophosphamide, fludarabine and antithymocyte globulin for sibling and unrelated transplant of children with severe and very severe aplastic anemia. Pediatr Transplant Chung NG aplastic anemia
04/02/2013 Methylation of Promoters of microRNAs and their Host Genes in Myelodysplastic Syndromes. Leuk Lymphoma Erdogan B myelodysplastic syndromes (MDS)
04/02/2013 The Myelodysplastic Syndromes (MDS): A personal recollection of four decades of classification and prognostic scoring systems. Leuk Lymphoma Bennett JM. myelodysplastic syndromes (MDS)