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  1. New therapeutic approaches for protecting hematopoietic stem cells in aplastic anemia.

    ... targets self-reactive T cells, or (2) matched sibling or unrelated BM transplant (BMT). The IST treatment is often not effective due to ... to their age, comorbidities, and the lack of histocompatible donor. This necessitates development and testing of novel approaches to reduce ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. Alemtuzumab with fludarabine and cyclophosphamide reduces chronic graft versus host disease after allogeneic stem cell transplantation for acquired aplastic anemia.

    ... transplanted from matched sibling donors (MSD) (n=21) and unrelated donors, UD (n=29), using fludarabine 30mg/m(2) for 4 days, ... graft failure was 9.5% for MSD and 14.5% for UD HCT. Full donor chimerism (FDC) in unfractionated peripheral blood was 42%; no patient ...

    Research Article last updated 07/20/2018 - 5:14pm.

  3. Hematopoietic stem cell transplantation with umbilical cord multipotent stromal cell infusion for the treatment of aplastic anemia-a single-center experience.

    ... human leukocyte antigen -matched related (six cases) and unrelated donors (eight cases). MSCs were intravenously infused at a mean dose ... 15 months; they are transfusion-independent and reached full donor chimerism at the time of reporting. CONCLUSIONS: UC-MSC infusion ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Total Lymphoid Irradiation-Antithymocyte Globulin Conditioning and Allogeneic Transplantation for Patients with Myelodysplastic Syndromes and Myeloproliferative Neoplasms

    ... globulin (ATG) permits the establishment of donor hematopoiesis necessary for the graft-versus-malignancy effect ... between patients who received allografts from related or unrelated donors. The cumulative incidence of nonrelapse mortality (NRM) at ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. MDS - Treatment (OLD)

    ... you receive a transfusion, the cell parts of blood from a donor are put into your bloodstream. This increases your blood counts and ... have a sibling match, you will need to find an matched unrelated donor (MUD) through a bone marrow donor registry like the one ...

    Topic section last updated 07/20/2018 - 5:15pm.

  6. Unmanipulated Haploidentical Hematopoietic Stem Cell Transplantation Achieved Outcomes Comparable With Matched Unrelated Donor Transplantation in Young Acquired Severe Aplastic Anemia

    ... with severe aplastic anemia (SAA) if a matched unrelated donor (MUD) is unavailable. However, studies on haplo- and MUD ...

    Research Article last updated 06/13/2018 - 2:28pm.

  7. Since my diagnosis, my mission has been to fight back

    ... my only sibling was my half-brother, the search for an unrelated donor match began. At the time, our youngest daughter was 14, and Stanford ...

    Patient Chronicle last updated 04/26/2018 - 10:40am.

  8. Transplant Experience Amplifies Her Desire for Research Career

    ... sickle cell anemia, and had a transplant from an unrelated donor . The hospital often held events like bingo or treasure hunts for the ...

    Patient Chronicle last updated 04/26/2018 - 12:47pm.

  9. Graft vs. Host Disease (GVHD)

    ... between 2 and 6 out of every 10 patients transplanted with donor cells will develop some level of GVHD after transplant. The chance of ... Patients who were transplanted with cells from an unrelated donor Patients transplanted with stem cells gathered ...

    Topic section last updated 04/30/2018 - 4:28pm.

  10. Retired MDS Patient Living Life to the Fullest Since Transplant

    ... a stem cell bone marrow transplant from an unrelated donor from the international registry!  I was in isolation at the Hospital ...

    Patient Chronicle last updated 04/26/2018 - 10:43am.