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  1. Diagnostic screening of paroxysmal nocturnal hemoglobinuria: Prospective multicentric evaluation of the current medical indications

    ... been submitted for PNH testing because of unexplained thrombosis in the absence of cytopenia , were positive (0.4%). ... screening algorithms are needed for patients presenting with thrombosis and normal blood cell counts. ...

    Research Article last updated 10/06/2016 - 8:56am.

  2. Keith McCrae, MD

    ... with PNH are at increased risk for the development of thrombosis , or blood clots, that may affect arteries or veins and cause ... One mechanism that may contribute to the development of thrombosis in PNH is the formation of microparticles. Microparticles are ...

    Grant Recipient last updated 02/27/2017 - 7:05am.

  3. Self-injected PNH therapy on the horizon

    ... well, which could help in preventing potentially fatal thrombosis among PNH patients. Soliris reduces thrombotic events, but maybe ...

    Article last updated 07/07/2016 - 9:40am.

  4. “Don’t worry, I’m not going anywhere.”

    ... blurred vision and has developed sleep apnea, deep vein thrombosis , and herniated and bulging neck and spine discs due to ...

    Patient Chronicle last updated 04/26/2018 - 10:18am.

  5. Symptoms

    ... Thrombosis Thrombosis is a blood clot in a vein. It is often simply called a ...

    Topic section last updated 03/29/2016 - 6:18pm.

  6. Antonio Maria Risitano, MD, PhD

    ... Pathophysiology , Clinical Manifestations (including Thrombosis ) and Response to Eculizamab PNH Foundation." We recently ...

    Bio last updated 10/20/2017 - 9:50am.

  7. Foundation Update - July 2016

    ... • PNH: Secondary Mutations and Thrombosis • Transitioning from Pediatric to Adult ...

    Article last updated 10/09/2017 - 2:53pm.

  8. Research and Education Council

    ... of bone marrow failure conditions (e.g., blood clotting/ thrombosis in PNH, iron overload in MDS, etc). Members ...

    Page last updated 06/20/2017 - 9:22am.

  9. Patrizia Ricci, PhD

    ... ), poor functioning of bone marrow , and thrombosis . Recently, the availability of the complement inhibitor ...

    Grant Recipient last updated 09/14/2016 - 2:42pm.

  10. Robert A. Brodsky, MD

    ... antibody eculizimab was developed to combat the thrombosis that constitutes a leading cause of death in PNH, but produces a ...

    Bio last updated 09/12/2016 - 11:04am.