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  1. Simona Pagliuca, MD

    ... ), white blood cells (leukopenia), and platelets ( thrombocytopenia ). If untreated, this disease has a high risk of death. ... ), white blood cells (leukopenia), and platelets ( thrombocytopenia ). If untreated, this disease has a high risk of severe ...

    Grant Recipient last updated 08/15/2018 - 12:22pm.

  2. Pathophysiology and management of thrombocytopenia in bone marrow failure: possible clinical applications of TPO receptor agonists in aplastic anemia and myelodysplastic syndromes.

    ... were developed to treat patients with refractory immune thrombocytopenia but are now being investigated for the treatment of bone ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Selective splenic artery embolization for the treatment of thrombocytopenia and hypersplenism in paroxysmal nocturnal hemoglobinuria

    ... The combination of thrombosis, splenomegaly, and thrombocytopenia (TST) is challenging because anticoagulants are indicated but thrombocytopenia may increase the bleeding risk. Splenectomy could alleviate ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Thrombocytopenia in patients with myelodysplastic syndromes.

    ... Thrombocytopenia , common in leukemias and myelodysplastic syndromes ... purpura (ITP), and are being explored for the treatment of thrombocytopenia in MDS. Bone ...

    Research Article last updated 07/20/2018 - 5:14pm.

  5. Thrombopoiesis-stimulating agents and myelodysplastic syndromes

    ... Thrombocytopenia in patients with myelodysplastic syndromes (MDS) ... transformation and reduced overall survival. In addition, thrombocytopenia in MDS limits the tolerability and therapeutic efficacy of ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Lenalidomide for del(5q) and Non-del(5q) Myelodysplastic Syndromes

    ... years, mainly at the expense of neutropenia and thrombocytopenia in the first courses of therapy. At present, the optimal ... response, and 50% incidence of grade 3 and 4 neutropenia and thrombocytopenia compared to del(5q) patients. Recent data suggest that the ...

    Research Article last updated 07/20/2018 - 5:14pm.

  7. Immunosuppressive therapy for transplant-ineligible aplastic anemia patients

    ... infection and hemorrhage due to neutropenia and thrombocytopenia and suffer from symptoms of anemia. The main treatment ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Use of azacitidine for myelodysplastic syndromes: controversial issues and practical recommendations.

    ... therapy or for patients with lower-risk MDS who have thrombocytopenia or neutropenia or have anemia that is ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Myelodysplastic syndromes: a challenging disease for patients and physicians

    ... high risk of rapidly developing neutropenia and thrombocytopenia . Several promising drugs are currently under investigation ...

    Research Article last updated 07/20/2018 - 5:14pm.

  10. Decreased plasma cytokines associate with low platelet counts in aplastic anemia and immune thrombocytopenic purpura

    ... than in those with lower platelet counts. In a murine thrombocytopenia model, levels of CD40L, CXCL5, CCL5, and EGF decreased ...

    Research Article last updated 07/20/2018 - 5:14pm.