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  1. Stem Cell Transplant for Juvenile Myelomonocytic Leukemia (JMML)

    ... monocytosis (> 1,000) The presence of immature myeloid cells in the peripheral blood Less than 30% marrow blasts ... Intervention:  Procedure: Stem Cell Transplant As part of the stem-cell transplant process, patients ...

    Clinical Trial last updated 07/14/2016 - 3:59pm.

  2. Coleman Lindsley, MD, PhD

    ... telomere length and telomerase gene mutations on allogeneic stem cell transplantation outcomes in myelodysplastic syndromes ... we propose to measure telomere length in the blood cells of MDS patients and correlate with clinical and genetic information. ...

    Grant Recipient last updated 06/05/2017 - 11:04am.

  3. How do I decide between antithymocyte globulin (ATG) and bone marrow transplant for treatment of aplastic anemia?

    ... anemia treatment is to increase the number of healthy cells in your blood so you will feel better, no longer need transfusions and ... from attacking your bone marrow , letting your stem cells grow back and raising your blood count. This is a standard ...

    FAQ last updated 03/15/2016 - 11:50pm.

  4. Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

    ... Purpose:  Allogeneic hematopoietic stem cell transplantation (aHSCT) can cure patients with a variety of bone ... contained approximately a 20 fold higher dose of T-cells that had undergone a TH- 2 type cytokine polarization, a factor which ...

    Clinical Trial last updated 04/25/2016 - 10:08am.

  5. Current Outcome of HLA Identical Sibling vs Unrelated Donor Transplants in Severe Aplastic Anemia: An EBMT Analysis

    ... R. Passweg, R. Oneto, and Judith Marsh Hematopoietic stem cell transplantation (HSCT) for severe aplastic anemia involves ... infusion of healthy blood-forming (hematopoietic) stem cells . Ideally, the healthy stem cells come from a sibling who has the same ...

    Research Review last updated 05/02/2016 - 9:20am.

  6. Interviews with the Experts: The Complement System in PNH

    ... pathogens. It also serves to draw in the immune system cells to clear all the dead tissues and byproducts of inflammation, and also ... of medicine and pathology, Section of Hematology and Stem Cell Transplantation, Division of Hematology/Oncology, at Rush University ...

    Interview last updated 08/31/2016 - 8:39am.

  7. Finding a Stem Cell Donor

    ... thinks you may be a candidate for a bone marrow / stem cell transplant in the future, start looking for a donor right away. ... ( HLA ) type. HLA are proteins found on most cells in your body. Your immune system uses these proteins as markers to ...

    Page last updated 05/14/2015 - 9:46am.

  8. Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)

    ... of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (HSCT). This study aims to determine if any of three ... and must be willing to donate peripheral blood stem cells and meet institutional criteria for donation. Unrelated donor ...

    Clinical Trial last updated 06/06/2016 - 1:59pm.

  9. Treatments

    ... A bone marrow transplant (BMT) is also called a stem cell transplant (SCT) or hematopoietic stem cell transplant (HSCT).The procedure replaces unhealthy blood-forming stem cells with healthy ones and offers some patients the possibility of a cure. But ...

    Topic section last updated 02/16/2017 - 3:04pm.

  10. Clinical Trials Report for January 2016

    ... Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies ... stem cell transplant may help stop the growth of cancer cells. It may also stop the patient's immune system from rejecting the donor's ...

    Page last updated 01/07/2016 - 10:57am.