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  1. Hematopoietic stem cell and progenitor cell mechanisms in myelodysplastic syndromes.

    ... and ineffective hematopoiesis . Hematopoietic stem cells (HSCs) and myeloid progenitors in MDS have not been extensively ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. First-line matched related donor hematopoietic stem cell transplantation compared to immunosuppressive therapy in acquired severe aplastic anemia.

    ... immune-mediated functional impairment of hematopoietic stem cells . Transplantation of these cells is a first-line treatment option if ...

    Research Article last updated 07/20/2018 - 5:14pm.

  3. Long-term follow-up after allogeneic stem cell transplantation in patients with severe aplastic anemia after cyclophosphamide plus antithymocyte globulin conditioning

    ... long-term follow-up of patients who underwent hematopoietic stem cell transplantation from an HLA -matched sibling donor after this ... but 2 received bone marrow as the source of stem cells and all but 2 engrafted. Cumulative incidence of acute grade II-IV ...

    Research Article last updated 07/20/2018 - 5:14pm.

  4. Disease progression in myelodysplastic syndromes: do mesenchymal cells pave the way?

    ... Journal Title:  Cell Stem Cell Primary Author:  ... permissive niche has been implicated. In this issue of Cell Stem Cell, Medyouf et al. (2014) provide insights into the role of the niche ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. A prospective multicenter study of paroxysmal nocturnal hemoglobinuria cells in patients with bone marrow failure.

    ... hemoglobinuria (PNH), a rare clonal hematopoietic stem cell disorder, is characterized by chronic, uncontrolled complement ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. A Prospective Multicenter Study of Paroxysmal Nocturnal Hemoglobinuria Cells in Patients with Bone Marrow Failure.

    ... hemoglobinuria (PNH), a rare clonal hematopoietic stem cell disorder, is characterized by chronic, uncontrolled complement ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Research in making blood stem cells in the lab advances

    ... Approaching a decades-old goal: Making blood stem cells from patients' own cells ...

    Article last updated 05/18/2017 - 7:18am.

  8. Laboratory tests for paroxysmal nocturnal hemoglobinuria (PNH).

    ... Glycan class A (PIG-A) gene in the hematopoietic stem cells (HSC) of patients. The presence of these mutations leads to ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Eltrombopag and improved hematopoiesis in refractory aplastic anemia

    ... cytopenia and a profound deficit in hematopoietic stem cells and progenitor cells. Thrombopoietin may increase the number of ...

    Research Article last updated 07/20/2018 - 5:14pm.

  10. Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells

    ... and isogenic karyotypically normal induced pluripotent stem cells (iPSCs) from hematopoietic cells of MDS patients and show that the ...

    Research Article last updated 07/20/2018 - 5:15pm.