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  1. Reduced intensity conditioning, combined transplantation of haploidentical hematopoietic stem cells and mesenchymal stem cells in patients with severe aplastic anemia

    ... of combined haploidentical hematopoietic stem cells (HSC) and mesenchymal stem cells (MSC) affected graft failure and graft-versus-host disease ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. How Bone Marrow and Stem Cell Transplants Work

    ... Article Link:  How Bone Marrow and Stem Cell Transplants Work ... having a bone marrow transplant or donating stem cells , what does it entail? What are the different types of bone marrow ...

    Article last updated 09/04/2018 - 11:54am.

  3. Bone marrow mesenchymal stem cells from aplastic anemia patients preserve functional and immune properties and do not contribute to the pathogenesis of the disease

    ... anemia cases remain idiopathic , and hematopoietic stem cell deficiency and impaired immune responses are hallmark underlying ... marrow failure in aplastic anemia. Mesenchymal stem/stromal cells constitute an essential component of the bone marrow hematopoietic ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. New therapeutic approaches for protecting hematopoietic stem cells in aplastic anemia.

    ... by development and expansion of self-reactive T cells. These T cells cause continuous destruction of hematopoietic stem cells (HSCs), progenitors, and mature blood cells, leading to severe ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Reduced intensity conditioning and co-transplantation of unrelated peripheral stem cells combined with umbilical cord mesenchymal stem/stroma cells for young patients with refractory severe aplastic anemia.

    ... of unrelated donor peripheral blood stem cells (UD-PBSCs) and umbilical cord mesenchymal/stroma stem cells (UC-MSCs). After FLU + CTX + ATG ± 2GY TBI conditioning, all ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Cotransplantation of allogeneic mesenchymal and hematopoietic stem cells in children with aplastic anemia

    ... here the preliminary results of allogeneic hematopoietic stem cell transplantation with mesenchymal stem cells (MSCs) for 6 cases of severe aplastic anemia . The patients ...

    Research Article last updated 07/20/2018 - 5:14pm.

  7. Impaired proliferative potential of bone marrow mesenchymal stem cells in patients with myelodysplastic syndromes is associated with abnormal WNT signaling pathway

    ... Journal Title:  Stem Cells Dev Primary Author:  ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. The different immunoregulatory functions of mesenchymal stem cells in patients with low-risk or high-risk myelodysplastic syndromes

    ... bone marrow disorders characterized by hematopoietic stem cell dysregulation and abnormalities in the immune system. Mesenchymal stem cells (MSC) have gained further interests after the demonstration of an ...

    Research Article last updated 07/20/2018 - 5:14pm.

  9. Functional characteristics of mesenchymal stem cells derived from bone marrow of patients with myelodysplastic syndromes

    ... Mesenchymal stem cells (MSCs) have emerged as excellent candidates for clinical application ...

    Research Article last updated 07/20/2018 - 5:14pm.

  10. CHIP – A Promising Genetic Discovery for MDS, AML and Cardiovascular Disease

    ... is new research that has shown how a buildup of mutated stem cells in the bone marrow may be a risk factor not only for hematologic ...

    Article last updated 08/30/2018 - 3:14pm.