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  1. AML study reports high response rates with combination targeted therapy

    ... Ib study of inhibitory drug therapy for relapsed or refractory acute myeloid leukemia (AML) have demonstrated a complete ...

    Article last updated 12/12/2017 - 8:29am.

  2. Selinexor With Fludarabine and Cytarabine for Treatment of Refractory or Relapsed Leukemia or Myelodysplastic Syndrome

    ... and cytarabine in pediatric patients with relapsed or refractory hematologic malignancies included acute myeloid leukemia (AML), ... with fludarabine and cytarabine in patients with relapsed or refractory hematologic malignancies ...

    Clinical Trial last updated 04/28/2016 - 9:48am.

  3. Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic Anemia

    ... Patients with relapsed or refractory SAA or very SAA defined: Bone marrow (< 25% ... Patients with inherited disease will be characterized as refractory and do not require immunosuppressive first. Age 0- upper ...

    Clinical Trial last updated 06/06/2016 - 2:42pm.

  4. Persistent elevation of plasma thrombopoietin levels after treatment in severe aplastic anemia

    ... therapy (IST) or IST and eltrombopag , and 10 IST- refractory patients who had received eltrombopag only, focusing on ...

    Research Article last updated 10/23/2017 - 11:19am.

  5. Increasing the effectiveness of hematopoiesis in myelodysplastic syndromes: erythropoiesis-stimulating agents and transforming growth factor-β superfamily inhibitors

    ... responses are often short-lived. In fact, many ESA- refractory patients harbor defects in late-stage erythropoiesis downstream ...

    Research Article last updated 10/23/2017 - 11:08am.

  6. 8-Chloro-Adenosine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

    ... (relapsed) or has not responded to previous treatment ( refractory ). Drugs used in chemotherapy , such as ...

    Clinical Trial last updated 05/23/2016 - 3:25pm.

  7. Study of IRX5183 in Relapsed and Refractory Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome

    ... the use of IRX5183 in 1) patients with relapsed and/or refractory AML and 2) patients with high-risk MDS or chronic myelomonocytic ...

    Clinical Trial last updated 04/29/2016 - 10:22am.

  8. ONC201 in Relapsed/Refractory Acute Leukemias and High-risk Myelodysplastic Syndromes (HR-MDS)

    ... of ONC201 that can be given to patients with relapsed or refractory AML, ALL, or MDS. The goal of Phase II of this study is to ...

    Clinical Trial last updated 04/29/2016 - 10:14am.

  9. A Study of BBI608 in Adult Patients With Advanced, Refractory Hematologic Malignancies

    ... study of BBI608 administered to patients with relapsed, refractory hematologic malignancies, including multiple myeloma, lymphoma, ...

    Clinical Trial last updated 04/28/2016 - 3:34pm.

  10. Safety and Effectiveness Study of CPI-613 to Treat Refractory or Relapsed Leukemia and Myelodysplastic Syndrome

    ... CPI-613 is effective and safe in either patients with refractory or relapsed acute myeloid leukemia (AML) or patients ...

    Clinical Trial last updated 04/28/2016 - 12:21pm.