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  1. Eltrombopag in aplastic anemia

    ... treatment of patients with severe aplastic anemia (SAA) refractory to IST. There is evidence that this drug works by directly ... combination therapy in the upfront treatment of SAA, in IST-refractory SAA and in moderate disease. ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. SF3B1 mutations in patients with myelodysplastic syndromes: the mutation is stable during disease evolution

    ... of 479 MDS patients and 61.8% of 34 patients with refractory anemia with ring sideroblasts (RARS). SF3B1 mutations ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Clinical activity and safety of the dual pathway inhibitor rigosertib for higher risk myelodysplastic syndromes following DNA methyltransferase inhibitor therapy

    ... by an external ambulatory infusion pump in patients with refractory anemia with excess blasts -1, -2, or, -t ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Distinct iron architecture in SF3B1 mutant myelodysplastic syndromes patients is linked to an SLC25A37 splice variant with a retained intron

    ... ring sideroblasts (RS). RS is a cardinal feature of refractory anemia with RS (RARS) and RARS with marked ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Horse antithymocyte globulin as salvage therapy after rabbit antithymocyte globulin for severe aplastic anemia

    ... plus cyclosporine (CsA) in patients who were refractory to initial r-ATG/CsA (n=19) or cyclophosphamide/CsA (n=6) ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Clofarabine in the treatment of myelodysplastic syndromes.

    ... the treatment of pediatric patients with relapsed or refractory acute lymphocytic leukemia (ALL) following failure of at least ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Outcome of patients activating an unrelated donor search for severe acquired aplastic anemia.

    ... usually started. This study analyzes the outcome of ATG- refractory SAA patients activating a VUD search. Of 179 patients, 68 had at ... use of unrelated donor HSCT in children and adults with IST-refractory SAA. Bone Marrow ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. ALLOGENEIC STEM CELL TRANSPLANTATION (HSCT) FOR ADULTS WITH MYELODYSPLASTIC SYNDROMES (MDS): RELEVANCE OF PRE-TRANSPLANT DISEASE STATUS.

    ... the time of transplant, 53 patients (56%) had relapsed/ refractory disease. The cumulative incidence of grades II-IV acute ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Haploidentical transplantation in patients with acquired aplastic anemia

    ... haplo-SCT for SAA. Haploidentical transplants for refractory SAA should be performed in a specialist center with major ...

    Research Article last updated 07/20/2018 - 5:15pm.

  10. The Myelodysplastic Syndromes (MDS): A personal recollection of four decades of classification and prognostic scoring systems.

    ... with myelodysplastic syndromes (MDS), namely refractory anemia with excess blasts (RAEB) and chronic ...

    Research Article last updated 07/20/2018 - 5:15pm.