Search | Aplastic Anemia and MDS International Foundation

Search

Search results

  1. Reduced intensity conditioning, combined transplantation of haploidentical hematopoietic stem cells and mesenchymal stem cells in patients with severe aplastic anemia

    ... donor-derived umbilical cord MSCs (UC-MSCs), respectively. Reduced intensity conditioning consisted of fludarabine (30 ... (500 mg/m2·d)+anti-human thymocyte IgG. Transplant recipients also received cyclosporin A, mycophenolatemofetil, and ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. Long-term outcome of fludarabine-based reduced intensity allogeneic hematopoietic cell transplantation for debilitating paroxysmal nocturnal hemoglobinuria

    ... including 8 who were HLA -alloimmunized, underwent a reduced intensity allogeneic hematopoietic cell transplant (HCT). All received ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Pilot trial of risk-adapted cyclophosphamide intensity based conditioning and HLA matched sibling and unrelated cord blood stem cell transplantation in newly diagnosed pediatric and adolescent recipients with acquired severe aplastic anemia

    ... been associated with decreased overall survival. Reduced toxicity conditioning and AlloHSCT has been used successfully in other ... transfusions received conditioning regimen with higher intensity cyclophosphamide (200 mg/kg). RESULTS: Seventeen patients ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Optimizing stem cell transplantation in myelodysplastic syndromes: unresolved questions.

    ... patient selection, and transplant modifications using reduced conditioning intensity. This review highlights strategies to optimize transplant for MDS ...

    Research Article last updated 07/20/2018 - 5:14pm.

  5. Hematopoietic stem cell transplantation for paroxysmal nocturnal hemoglobinuria: long-term results of a retrospective study on behalf of the Gruppo Italiano Trapianto Midollo Osseo (GITMO).

    ... (in all cases from identical donor) and 11 were given a reduced intensity conditioning (8 from identical donor and 3 from mismatched donor). ...

    Research Article last updated 07/20/2018 - 5:14pm.

  6. Allogeneic Hematopoietic Cell Transplantation for Myelodysplastic Syndromes - Lingering Uncertainties and Emerging Possibilities

    ... increasing age of allogeneic recipients, introduction of reduced intensity conditioning (RIC) regimens, increased availability of unrelated ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Hematopoietic stem cell transplantation for older patients with myelodysplastic syndromes.

    ... older than 60 years, typically only conditioning regimens of reduced intensity are used. However, although these regimens are associated with little ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Reduced-intensity hematopoietic cell transplantation in older patients with AML/MDS: umbilical cord blood is a feasible option for patients without HLA-matched sibling donors

    ... myelodysplastic syndromes (MDS). All patients received a reduced intensity regimen consisting of CY, fludarabine and 200 cGy TBI. ...

    Research Article last updated 07/20/2018 - 5:14pm.

  9. Outcomes after Umbilical Cord Blood Transplantation for Myelodysplastic Syndromes

    ... associated with TRM (P=.001), DFS (P=.02), and OS (P=.001). Reduced conditioning intensity was associated with increased risk of relapse (RR 3.95; 95% CI ...

    Research Article last updated 03/22/2017 - 9:24am.

  10. Allogeneic stem cell transplantation in myelodysplastic syndromes: does pretransplant clonal burden matter?

    ... for cytoreductive therapy before transplant, especially if reduced intensity conditioning (alloSCT) is planned. Patients with less than 10% blasts ...

    Research Article last updated 04/29/2016 - 10:22am.