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  1. PNH: Understanding Hemolytic Anemia, Pancytopenia, and Thrombosis

    ... three things: Hemolytic anemia (destruction of red blood cells) Pancytopenia (low counts for all blood cell types) ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  2. PNH: Understanding Hemolytic Anemia, Pancytopenia, and Thrombosis

    ... three things: Hemolytic anemia (destruction of red blood cells) Pancytopenia (low counts for all blood cell types) ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  3. Aplastic Anemia 101: Understanding Diagnosis and Treatment

    ... that happens when the bone marrow stops making enough red blood cells, white blood cells and platelets for the body. Aplastic anemia can ...

    LMS Item last updated 06/10/2016 - 1:24pm.

  4. Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

    ... compared to filgrastim (G-CSF) mobilized peripheral blood stem cell (PBSC) transplants, BM allografts have lower CD34+ progenitor ... 2) Severe aplastic anemia (SAA) or pure red cell aplasia (PRCA [acquired or congenital]) associated with transfusion ...

    Clinical Trial last updated 04/28/2016 - 2:40pm.

  5. What are low blood counts?

    When you have a low blood count, this means your bone marrow is not making enough of ... cell in your blood sample. If the CBC shows a low number of red blood cells, white blood cells, or platelets, your doctor may look at the ...

    FAQ last updated 04/28/2016 - 4:47pm.

  6. Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Hematologic Malignancies Undergoing Donor Peripheral Blood Stem Cell Transplant

    ... with hematologic malignancies undergoing donor peripheral blood stem cell (PBSC) transplant. Giving chemotherapy and total-body ... may help the patient's bone marrow make stem cells, red blood cells, white blood cells, and platelets. Sometimes the transplanted ...

    Clinical Trial last updated 04/28/2016 - 12:07pm.

  7. Total Marrow Irradiation for Refractory Acute Leukemia

    ... and total marrow irradiation before a donor umbilical cord blood or hematopoietic stem cell transplant helps stop the growth of ... may help the patient's bone marrow make stem cells, red blood cells, white blood cells, and platelets. Sometimes the transplanted ...

    Clinical Trial last updated 05/02/2016 - 9:22am.

  8. Yue Wei, Ph.D.

    ... or variation in the development of types of blood cells. In recent work that compared bone marrow of MDS and non MDS ... they could increase the number of erythroid or immature red blood cell colonies in samples of bone marrow from low risk MDS patients, through ...

    Bio last updated 03/11/2016 - 1:41pm.

  9. Novel Complement Modulators for Paroxysmal Nocturnal Hemoglobinuria: Peptide and Protein Inhibitors of C3 Convertase Prevent Both Surface C3 Deposition and Subsequent Hemolysis of Affected Erythrocytes in Vitro

    ... on later. Eventually a pore is formed in the surface of the red cell from patients with PNH which causes the cell to break open. Eculizumab ... might prevent both types of hemolysis (breakdown in the blood vessels and extravascular hemolysis) and might be more effective than ...

    Research Review last updated 05/02/2016 - 9:25am.

  10. MDS Drug Therapy

    ... had some positive response to treatment, meaning that blood counts went up. The percentage of patients still surviving after two ... fewer transfusions Were more likely to have improved red blood cell counts Experienced a delay in MDS progressing to ...

    Topic section last updated 03/10/2016 - 11:26pm.