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  1. Long-term follow-up of patients with moderate aplastic anemia and pure red cell aplasia treated with daclizumab.

    ... BACKGROUND: Pure red cell aplasia and moderate aplastic anemia are marrow failure ... Previously, we described short-term improvements in blood counts in two pilot studies treating moderate aplastic anemia (mAA) and ...

    Research Article last updated 07/20/2018 - 5:14pm.

  2. What is Flow Cytometry?

    ... that helps certain proteins to stick to the surface of blood cells. Therefore, any blood cells created by this mutated bone marrow ... or all of two proteins (CD55 and CD59) on the surface of red blood cells, which causes the cells to break apart. This process is known ...

    Article last updated 10/10/2018 - 8:08am.

  3. Performance characteristics of consensus approaches for small and minor paroxysmal nocturnal hemoglobinuria clone determination by flow cytometry.

    ... (1%-20%) and minor (<1%) PNH clones within the white blood cell (WBC) and red blood cell (RBC) compartments with sensitivity up to 0.1%. Results: ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Polymorphism of the complement receptor 1 gene correlates with hematological response to eculizumab in patients with paroxysmal nocturnal hemoglobinuria

    ... the response is variable and some patients remain red blood cell transfusion -dependent. In 72 patients with hemolytic Paroxysmal ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Treatment and outcomes for chronic myelomonocytic leukemia compared to myelodysplastic syndromes in older adults

    ... to Medicare claims. Baseline characteristics, treatment ( red blood cell transfusions, hematopoietic growth factors, hypomethylating ...

    Research Article last updated 07/20/2018 - 5:14pm.

  6. Iron overload in myelodysplastic syndromes: diagnosis and management.

    ... stem cell malignancies characterized by ineffective blood cell production. Many MDS patients are dependent on red blood cell (RBC) transfusions for symptomatic management of ...

    Research Article last updated 07/20/2018 - 5:14pm.

  7. Costs and quality of life in patients with myelodysplastic syndromes.

    ... Journal Title:  Am J Blood Res Primary Author:  ... most MDS patients become anaemic, so as to require red blood cell transfusions. To investigate the costs and the impact on ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Impact of iron overload in myelodysplastic syndromes.

    ... Journal Title:  Blood Rev Primary Author:  ... (MDS), and most patients with MDS receive regular red blood cell transfusions, which can lead to iron overload . Some ...

    Research Article last updated 07/20/2018 - 5:14pm.

  9. Clinical utility of lenalidomide in the treatment of myelodysplastic syndromes

    ... Journal Title:  J Blood Med Primary Author:  ... of patients with del(5q) MDS, including reduction in red blood cell transfusion requirements and improvements in quality of ...

    Research Article last updated 07/20/2018 - 5:15pm.

  10. How we treat lower risk myelodysplastic syndromes.

    ... Journal Title:  Blood Primary Author:  ... in most cases. Supportive care , mainly red blood cell transfusions, remains an important component of their ...

    Research Article last updated 07/20/2018 - 5:15pm.