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  1. Luspatercept for the treatment of anaemia in patients with lower-risk myelodysplastic syndromes (PACE-MDS): a multicentre, open-label phase 2 dose-finding study with long-term extension study

    ... chronic myelomonocytic leukaemia ( white blood cell count <13 000/μL), and had anaemia with or without red blood cell transfusion support. Enrolled patients were classified as ...

    Research Article last updated 09/18/2017 - 1:38pm.

  2. Early treatment initiation in lower-risk myelodysplastic syndromes produces an earlier and higher rate of transfusion independence

    ... resulting in refractory cytopenias. Red blood cell (RBC) transfusions can improve anemia ; however, prolonged ...

    Research Article last updated 09/13/2017 - 8:58am.

  3. Prophylactic RhCE and Kell antigen matching: impact on alloimmunization in transfusion-dependent patients with myelodysplastic syndromes

    ... (MDS) become transfusion-dependent and are at risk for red blood cell (RBC) alloimmunization. This study compared alloimmunization ...

    Research Article last updated 02/03/2017 - 11:00am.

  4. Alternative Donor Transplantation with High-Dose Post-Transplantation Cyclophosphamide for Refractory Severe Aplastic Anemia

    ... Journal Title:  Biol Blood Marrow Transplant Primary ... for 3 consecutive days was 19 (range, 16 to 27) days, to red cell engraftment was 25 (range, 2 to 58) days, and to last ...

    Research Article last updated 01/24/2017 - 10:04am.

  5. Red Blood Cell Transfusion Dependency and Hyperferritinemia Are Associated with Impaired Survival in Patients Diagnosed with Myelodysplastic Syndromes: Results from the First Polish MDS-PALG Registry

    ... analysis of the relationship of SF concentration with red blood cell transfusion dependency, survival and transformation to acute ...

    Research Article last updated 10/06/2016 - 1:01pm.

  6. Efficacy and Safety of Lenalidomide for Treatment of Low-/Intermediate-1-Risk Myelodysplastic Syndromes with or without 5q Deletion: A Systematic Review and Meta-Analysis

    ... Lenalidomide could effectively induce red blood cell (RBC) transfusion independence (TI) in patients with ...

    Research Article last updated 11/28/2016 - 9:36am.

  7. Eltrombopag Added to IST Yields Encouraging Results

    ... improvement in platelet counts but also noticed recovering red and white blood cells numbers. Although the magnitude of the response was somewhat ...

    Interview last updated 05/24/2017 - 7:44am.

  8. AAMDSIF Summer Fellowship Grant Program

    ... (BM) characterized by profound decrease of the number of red blood cells, white blood cells, and platelets in the blood stream, leading to ...

    Page last updated 05/17/2017 - 1:29pm.

  9. Transfusion Thresholds, Quality of Life, and Current Approaches in Myelodysplastic Syndromes

    ... Hemoglobin thresholds and triggers for blood transfusions have changed over the years moving from a higher to a lower ... clinical trials are looking for a more liberal approach of red cell transfusion and the effect on quality of life as opposed to the ...

    Research Article last updated 06/23/2016 - 9:55am.

  10. Design and rationale of the QUAZAR Lower-Risk MDS (AZA-MDS-003) trial: a randomized phase 3 study of CC-486 (oral azacitidine) plus best supportive care vs placebo plus best supportive care in patients with IPSS lower-risk myelodysplastic syndromes and po

    ... and/or thrombocytopenia who may have required red blood cell or platelet transfusions. The overall response rate was ...

    Research Article last updated 06/23/2016 - 10:17am.