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  1. A Phase II Study of the Combination of Azacitidine and Pembrolizumab for Patients with Myelodysplastic Syndrome (MDS)

    ... to give informed consent to comply with the study protocol or to complete the study. Any severe or concurrent disease or ...

    Clinical Trial last updated 05/14/2018 - 1:57pm.

  2. Learning about Clinical Trials Part 1: Do You Know How to Read a Study Record?

    ... diseases. Each clinical trials will have a protocol or written description of the clinical study. A protocol includes the study's objectives, design, and methods. It may also ...

    Page last updated 05/14/2015 - 2:03pm.

  3. A Phase III, International, Randomized, Controlled Study of Rigosertib versus Physician’s Choice of Treatment in Patients with Myelodysplastic Syndrome after Failure of a Hypomethylating Agent

    ... to the prohibitions and restrictions specified in this protocol l.  Patients (or, in case of patients who are incapable, the ...

    Clinical Trial last updated 05/04/2018 - 3:53pm.

  4. Myeloablative Unrelated Donor Cord Blood Transplantation With T-Cell Depleted Haplo-identical Peripheral Blood Stem Cells for Patients With High Risk Hematological Malignancies

    ... Inclusion Criteria:  Note: protocol eligible patients according to the criteria outlined below will ... If 200 cGy of prior TBI then only 400 CGy of TBI on this protocol is permitted. Uncontrolled viral, bacteria or fungal infection ...

    Clinical Trial last updated 04/29/2016 - 1:33pm.

  5. Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

    ... contributed to this high incidence of cGVHD. In this protocol , we attempt to prevent graft failure and to reduce the incidence ... using the identical conditioning regimen utilized in protocol 99-H-0050. Using the Miltenyi CliniMACs system, recipients will ...

    Clinical Trial last updated 04/28/2016 - 2:40pm.

  6. Clinical Trial Basics

    ... research is done according to a detailed plan known as a protocol . The protocol is carefully designed to safeguard the participants’ health and answer specific research questions. A protocol describes the following: Who is eligible to participate in ...

    Page last updated 03/29/2016 - 7:29pm.

  7. Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplant

    ... (AML) with disease features as described in the protocol . Acute lymphoblastic leukemia (ALL) with disease features as described in the protocol. Myelodysplasia with disease features as described in the ...

    Clinical Trial last updated 06/06/2016 - 3:37pm.

  8. Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC Transplant

    ... (AML) with disease features as described in the protocol . Acute lymphoblastic leukemia (ALL) with disease features as described in the protocol. Myelodysplasia with disease features as described in the ...

    Clinical Trial last updated 06/03/2016 - 2:54pm.

  9. GVHD Prophylaxis With Post Transplant Cyclophosphamide for Patients With Renal Insufficiency Undergoing a Conventional 8/8 HLA-matched Related or Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplant

    ... for autologous transplant or a higher priority protocol . Myelodysplastic syndrome (MDS): RA/RCMD with high risk ... evolved from MDS, who are not eligible for a higher priority protocol. Chronic myelomonocytic leukemia: CMML-1 and CMML-2, advanced ...

    Clinical Trial last updated 04/29/2016 - 12:40pm.

  10. CD34+ Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation for Non-Malignant Disease

    ... illness and the investigational nature of the study protocol (including foreseeable risks and possible side effects), and must ... Human Services. Approval for the use of this treatment protocol by the individual institution's Human Rights Committee must be ...

    Clinical Trial last updated 06/13/2016 - 2:06pm.