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  1. Hematopoietic stem cell transplantation with umbilical cord multipotent stromal cell infusion for the treatment of aplastic anemia-a single-center experience.

    ... The purpose of this study was to observe the outcome of co-transfusion of umbilical cord multipotent stromal cells (UC-MSC) and allogeneic ... rapid engraftment; mean time for neutrophil and platelet recovery was 13.95 d and 20.27 d, respectively. No acute toxicity ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. Eculizumab in Pregnant Patients with Paroxysmal Nocturnal Hemoglobinuria

    ... (8%) occurred during the first trimester. Requirements for transfusion of red cells increased during pregnancy, from a mean of 0.14 units ... pregnancy to 0.92 units per month during pregnancy. Platelet transfusions were given in 16 pregnancies. In 54% of pregnancies ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Diagnosis and treatment of pediatric acquired aplastic anemia (AAA): An initial survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC)

    ... of IST; the use of specific hemoglobin and platelet levels as triggers for transfusion support; the use of prophylactic antibiotics; and follow-up ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. A Phase 1 Study of Oral ARRY-614, a p38 MAPK/Tie2 Dual Inhibitor, in Patients with Low or Intermediate 1 Risk Myelodysplastic Syndromes

    ... patients experiencing bilineage responses. Three of 25 RBC transfusion-dependent (TD) patients achieved transfusion independence (TI) and 5 of 7 platelet TD patients achieved TI. Conclusions: ARRY-614 was well tolerated ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. My Life is Making a Difference

    ... began to respond. By the end of May, I had my last red cell transfusion and by early June had my last platelet transfusion . One side effect of treatment with cyclosporine is ...

    Patient Chronicle last updated 04/26/2018 - 10:20am.

  6. Aplastic Anemia Patient “Just Focused on Beating It”

    ... she thought I might have leukemia. She told me I needed a transfusion (my platelet count was 56). I was so upset I could not speak. I asked her to ...

    Patient Chronicle last updated 04/26/2018 - 12:49pm.

  7. My Encounter with Aplastic Anemia

    ... turned into hospitals, weekly red blood cell and platelet transfusions, and lots of fear. I was treated at Barnes Jewish ... I responded better, and my counts were able to stay above transfusion level for a little over a year. T.J. and I got married in 2009 and ...

    Patient Chronicle last updated 04/26/2018 - 10:16am.

  8. Updates from John and Isabella!

    ... take longer to come back, so that’s still a daily transfusion. We’re getting some numbers also about the current ratios of the ... to know this. The CMV medicine negatively affected his platelet counts for a while, but nothing else. So besides that, his counts ...

    Patient Chronicle last updated 04/26/2018 - 12:08pm.

  9. Aplastic anemia during pregnancy: a review of obstetric and anesthetic considerations

    ... outcomes, and plan peripartum interventions. Conservative transfusion management is critical to prevent alloimmunization. Although a safe threshold- platelet count for neuraxial anesthesia has not been established, selection ...

    Research Article last updated 04/11/2018 - 11:12am.

  10. Since my diagnosis, my mission has been to fight back

    ... I received numerous blood transfusions and over 100 platelet transfusions. Eventually, things started turning around. Our ... completed my 34th cycle of azacitidine and have not needed a transfusion in over 2 1/2 years. It has now been four years since my relapse, ...

    Patient Chronicle last updated 04/26/2018 - 10:40am.