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  1. What are the different components of blood?

    ... Blood is made of blood cells floating in plasma . The plasma is mostly made of water with chemicals in it. These chemicals include ...

    FAQ last updated 01/04/2018 - 12:05pm.

  2. Persistent elevation of plasma thrombopoietin levels after treatment in severe aplastic anemia

    ... dynamic change over time after treatment. We examined plasma concentrations of hematopoietic growth factors sequentially in 55 ... noted between TPO levels and platelet counts. The increased plasma TPO levels could be required to maintain normal platelet counts in ...

    Research Article last updated 10/23/2017 - 11:19am.

  3. Persistent elevation of plasma thrombopoietin levels after treatment in severe aplastic anemia

    ... dynamic change over time post treatment. We examined plasma concentrations of hematopoietic growth factors sequentially in 55 ... noted between TPO levels and platelet counts. The increased plasma TPO levels could be required to maintain normal platelet counts in ...

    Research Article last updated 10/02/2017 - 9:40am.

  4. Population pharmacokinetics of fludarabine in patients with aplastic anemia and Fanconi anemia undergoing allogeneic hematopoietic stem cell transplantation.

    ... NT5E gene (rs2295890 G>C) exhibited significantly lower plasma F-araA clearance compared to those with wild-type genotype (7.12 vs ... and multivariate analysis (P=0.02). The influence of plasma F-araA levels need to be evaluated in a larger cohort of patients to ...

    Research Article last updated 05/22/2017 - 10:32am.

  5. Drug reduces acute GVHD in unrelated HSCTs

    ... who did not receive vorinostat (P = .026). Day 30 plasma levels of inflammatory cytokines interleukin (IL)-6 and IL-10 were ...

    Article last updated 02/27/2017 - 1:45pm.

  6. Efficacy, safety, and pharmacokinetics of subcutaneous azacitidine in Taiwanese patients with higher-risk myelodysplastic syndromes

    ... (N = 12) and North American (N = 45) patients. Maximum plasma concentration was higher in Taiwanese patients; however, mean ...

    Research Article last updated 02/03/2017 - 10:05am.

  7. A plasma microRNA signature as a biomarker for acquired aplastic anemia

    ... monitor the disease. We analyzed circulating miRNAs in plasma samples of aplastic anemia patients in order to identify ... miRNAs. A total of 179 miRNAs were analyzed in 35 plasma samples from 13 aplastic anemia, 11 myelodysplastic syndrome, and 11 healthy controls using the Serum/Plasma Focus microRNA PCR Panel. Subsequently, 19 miRNAs from the discovery set ...

    Research Article last updated 10/06/2016 - 9:39am.

  8. The prognostic value of serum C-reactive protein, ferritin, and albumin prior to allogeneic transplantation for acute myeloid leukemia and myelodysplastic syndromes

    ... were centrally quantified by ELISA from cryopreserved plasma whereas each center provided pre-transplant albumin. In multivariate ...

    Research Article last updated 11/28/2016 - 9:44am.

  9. Positive Impact of Eculizumab Therapy on Surgery for Budd-Chiari Syndrome in a Patient with Paroxysmal Nocturnal Hemoglobinuria and a Long-Term History of Thrombosis

    ... gastrointestinal bleeding, hematuria, and elevated plasma lactate dehydrogenase ; he started eculizumab therapy ...

    Research Article last updated 11/02/2016 - 2:49pm.

  10. Extravascular hemolysis and complement consumption in Paroxysmal Nocturnal Hemoglobinuria patients undergoing eculizumab treatment

    ... C5 polymorphisms and evaluated for free eculizumab in plasma . We report that 10 patients (83%) present parameters suggesting ... CR1-L allele results in abnormally decreased levels of C3 in plasma that could, potentially, increase their susceptibility to bacterial ...

    Research Article last updated 10/06/2016 - 8:50am.