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  1. HLA-Compatible Related or Unrelated Donors With CD34+ Enriched, T-cell Depleted Peripheral Blood Stem Cells Isolated by the CliniMACS System in the Treatment of Patients With Hematologic Malignancies

    ... of using a system called CliniMACS to remove Tcells from blood stem cells . Removing T-cells may help stop a side effect called ...

    Clinical Trial last updated 04/29/2016 - 3:18pm.

  2. CD34+ Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation for Non-Malignant Disease

    ... this study the investigators are offering to treat the donor peripheral blood stem cells in the hope that it will make it less likely for the ...

    Clinical Trial last updated 04/27/2016 - 8:55am.

  3. Palifermin With Leuprolide Acetate for the Promotion of Immune Recovery Following Total Body Irradiation Based T-Cell Depleted Allogeneic Hematopoietic Stem Cell Transplantation

    ... recover faster following a stem cell transplant . Blood stem cells are very young blood cells that grow in the body to ... hemoglobin ) Patients have a plan to receive a peripheral blood stem cell collection. Patients must have no change in ...

    Clinical Trial last updated 04/29/2016 - 1:11pm.

  4. Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Hematologic Malignancies Undergoing Donor Peripheral Blood Stem Cell Transplant

    ... in patients with hematologic malignancies undergoing donor peripheral blood stem cell (PBSC) transplant. Giving chemotherapy and total-body ...

    Clinical Trial last updated 04/28/2016 - 12:07pm.

  5. Randomized Trial of Lenalidomide, Bortezomib, Dexamethasone vs High-Dose Treatment With SCT in MM Patients up to Age 65 (DFCI 10-106)

    ... syndrome (another type of cancer affecting the blood). Dexamethasone is commonly used, either alone, or in combination with ... to comply with an anti-thrombotic treatment regimen Peripheral neuropathy >/= Grade 2 ...

    Clinical Trial last updated 05/23/2016 - 3:45pm.

  6. Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

    ... Patients undergo cluster of differentiation (CD)34+ peripheral blood stem cell transplant on day 0. GVHD PROPHYLAXIS: Patients receive ...

    Clinical Trial last updated 04/27/2016 - 1:37pm.

  7. Organ-Sparing Marrow-Targeted Irradiation Before Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies

    ... allogeneic bone marrow transplantation Undergo allogeneic peripheral blood progenitor cell or bone marrow transplant on day 0 Other Names: bone ...

    Clinical Trial last updated 05/03/2016 - 11:29am.

  8. Shorter Course Tacro After NMA, Related Donor PBSCT With High-dose Posttransplant Cy for Hard-to-Engraft Malignancies

    ... it is possible to use short-duration tacrolimus after a peripheral blood stem cell transplant in certain malignancies that are considered ...

    Clinical Trial last updated 05/03/2016 - 11:45am.

  9. Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies

    ... transplantation (HSCT) Undergo allogeneic PBSCT Procedure: Peripheral blood stem cell transplantation Undergo allogeneic PBSCT Other Names: PBPC ...

    Clinical Trial last updated 05/03/2016 - 10:51am.

  10. Yttrium Y 90 Anti-CD45 Monoclonal Antibody BC8 Followed by Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome

    ... (FLU), and total-body irradiation (TBI) before a donor peripheral blood stem cell (PBSC) or bone marrow transplant helps stop the growth ...

    Clinical Trial last updated 04/28/2016 - 1:11pm.