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  1. Paroxysmal nocturnal hemoglobinuria from bench to bedside

    ... Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematologic disease that presents ...

    Research Article last updated 07/20/2018 - 5:14pm.

  2. Chronic treatment of paroxysmal nocturnal hemoglobinuria patients with eculizumab: safety, efficacy, and unexpected laboratory phenomena

    ... the standard of treatment in patients with symptomatic paroxysmal nocturnal hemoglobinuria (PNH). In this retrospective study, 19 PNH ...

    Research Article last updated 07/20/2018 - 5:14pm.

  3. Paroxysmal nocturnal hemoglobinuria in pediatric patients.

    ... BACKGROUND: Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disease in children. The most ...

    Research Article last updated 07/20/2018 - 5:14pm.

  4. Complement C3dg-mediated erythrophagocytosis: implications for paroxysmal nocturnal hemoglobinuria

    ... The clinical management of paroxysmal nocturnal hemoglobinuria (PNH), a rare but life-threatening ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Efficacy and safety of eculizumab in children and adolescents with paroxysmal nocturnal hemoglobinuria

    ... BACKGROUND: Paroxysmal nocturnal hemoglobinuria (PNH) is rare in children, but represents a ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Assessing complement blockade in patients with paroxysmal nocturnal hemoglobinuria receiving eculizumab

    ... Paroxysmal nocturnal hemoglobinuria (PNH) is characterized by intravascular ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Deep sequencing reveals stepwise mutation acquisition in paroxysmal nocturnal hemoglobinuria

    ... Paroxysmal nocturnal hemoglobinuria (PNH) is a nonmalignant clonal disease of ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Loss of expression of neutrophil proteinase-3: a contributory factor in thrombotic risk in paroxysmal nocturnal hemoglobinuria.

    ... specific glycosylphosphatidyl inositol-anchored proteins in paroxysmal nocturnal hemoglobinuria may be responsible for most of the clinical ...

    Research Article last updated 07/20/2018 - 5:14pm.

  9. Evaluation of hemostasis and endothelial function in patients with paroxysmal nocturnal hemoglobinuria receiving eculizumab.

    ... BACKGROUND: Paroxysmal nocturnal hemoglobinuria (PNH) is associated with an increased risk of ...

    Research Article last updated 07/20/2018 - 5:14pm.

  10. Paroxysmal nocturnal hemoglobinuria and other complement-mediated hematological disorders

    ... complement-mediated damage in several human diseases. Paroxysmal nocturnal hemoglobinuria (PNH) may be considered the paradigm a disease ...

    Research Article last updated 07/20/2018 - 5:14pm.