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  1. Loss of expression of neutrophil proteinase-3: a contributory factor in thrombotic risk in paroxysmal nocturnal hemoglobinuria.

    ... co-localizes with glycosylphosphatidyl inositol -linked neutrophil antigen B1, absent in patients with paroxysmal nocturnal ... and Methods: We compared expression of proteinase 3 and neutrophil antigen B1 by flow cytometry and western blotting in normal ...

    Research Article last updated 07/20/2018 - 5:14pm.

  2. Granulocyte transfusions in severe aplastic anemia: an eleven-year experience.

    ... granulocyte therapy, and post-transfusion absolute neutrophil count, stratified by HLA alloimmunization status. ... with survival. The mean post-transfusion absolute neutrophil count did not differ significantly between response groups (i.e. ...

    Research Article last updated 07/20/2018 - 5:14pm.

  3. Prediction of adverse events during Intensive Induction chemotherapy for acute myeloid leukemia or high-grade myelodysplastic syndromes

    ... baseline grade 4 neutropenia (i.e. absolute neutrophil count <500 cells/µL) was associated with development of fever ... cycle, grade 4 neutropenia was associated with delayed neutrophil count recovery (P<0.0001). Low monocyte and lymphocyte ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. A combination of fludarabine, half-dose cyclophosphamide, and anti-thymocyte globulin is an effective conditioning regimen before allogeneic stem cell transplantation for aplastic anemia

    ... one, who died due to encephalopathy on day 20, achieved neutrophil engraftment a median of 18.5 days after HSCT with ... regimen with half-dose CY and FDR is effective for achieving neutrophil engraftment and complete donor-type chimerism. However, subsequent ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Good outcome of haploidentical hematopoietic SCT as a salvage therapy in children and adolescents with acquired severe aplastic anemia

    ... from unrelated umbilical cord were infused on day 1. Neutrophil engraftment was achieved in all 17 patients in a median ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Epidemiology and risk factors for infections in myelodysplastic syndromes.

    ... = 2.7, 95% CI = 1.7-4.1, P < 0.0001), nadir absolute neutrophil count <500/mL (HR = 1.8, 95% CI = 1.2-2.7, P < 0.007), chronic ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Excellent Outcome of Haploidentical Hematopoietic Stem Cell Transplantation in Children and Adolescents with Acquired Severe Aplastic Anemia

    ... 2009 and July 2012. Among the 12 patients, 11 achieved neutrophil engraftment at a median of 10 days (range, 9 to 13 days) ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Reduced dose cyclophosphamide, fludarabine and antithymocyte globulin for sibling and unrelated transplant of children with severe and very severe aplastic anemia.

    ... UD, and 10 mismatched UD). All patients showed neutrophil and platelet engraftment . Cumulative incidence ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. Infections in myelodysplastic syndromes: a review

    ... immune defects have been reported, including impaired neutrophil function, B-, T-, and NK-cell defects and the possible ...

    Research Article last updated 07/20/2018 - 5:14pm.

  10. Comparison of Outcomes after Transplantation of G-CSF-Stimulated Bone Marrow Grafts versus Bone Marrow or Peripheral Blood Grafts from HLA-Matched Sibling Donors for Patients with Severe Aplastic Anemia.

    ... Transplantations occurred in 1997 to 2003. Rates of neutrophil and platelet recovery were not different among the 3 ...

    Research Article last updated 07/20/2018 - 5:14pm.