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  1. Outlook and Management of Patients with Myelodysplastic Syndromes Failed by Hypomethylating Agents.

    ... therapies for patients with higher-risk myelodysplastic syndromes (MDS). However, azacitidine and decitabine are not curative, the ...

    Research Article last updated 07/20/2018 - 5:15pm.

  2. p53 protein expression independently predicts outcome in patients with lower-risk myelodysplastic syndromes with del(5q)

    ... Low- or Intermediate-1-risk (lower-risk) del(5q) myelodysplastic syndromes are considered to have an indolent course; however, recent data ... demonstrated that 18% of patients with lower-risk del(5q) myelodysplastic syndromes carry TP53 mutated subclones rendering them at ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Recent developments in myelodysplastic syndromes

    ... Once thought to be rare disorders, the myelodysplastic syndromes (MDS) are now recognized as among the most common hematological ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes

    ... neoplasia and increased all-cause mortality. While myelodysplastic syndromes (MDS) are defined by cytopenias, dysplastic morphology ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Myelodysplastic syndromes: What do hospitalists need to know?

    ... Myelodysplastic syndromes (MDS) comprise a heterogeneous group of clonal hematopoietic stem ...

    Research Article last updated 07/20/2018 - 5:15pm.

  6. Incidence and Burden of the Myelodysplastic Syndromes

    ... Since 2001, cases of myelodysplastic syndromes (MDSs) have been tracked by cancer registries. Examining ...

    Research Article last updated 07/20/2018 - 5:15pm.

  7. Clinical and biological implications of driver mutations in myelodysplastic syndromes.

    ... Myelodysplastic syndromes (MDS) are a heterogeneous group of chronic hematological ...

    Research Article last updated 07/20/2018 - 5:15pm.

  8. Genetic and epigenetic pathways in myelodysplastic syndromes: A brief overview

    ... Myelodysplastic syndromes (MDS) are a highly heterogenous group of hematopoietic tumors, ...

    Research Article last updated 07/20/2018 - 5:15pm.

  9. The small population of PIG-A mutant cells in myelodysplastic syndromes do not arise from multipotent hematopoietic stem cells

    ... . Many patients with aplastic anemia and myelodysplastic syndromes also harbor small populations of ... evolve into paroxysmal nocturnal hemoglobinuria; however, myelodysplastic syndromes seldom evolve into paroxysmal nocturnal ...

    Research Article last updated 07/20/2018 - 5:14pm.

  10. Plasma circulating-microRNA profiles are useful for assessing prognosis in patients with cytogenetically normal myelodysplastic syndromes

    ... Myelodysplastic syndromes are a heterogeneous group of clonal bone marrow hematopoietic ...

    Research Article last updated 07/20/2018 - 5:15pm.