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  1. A Safety and Pharmacology Study of Atezolizumab (MPDL3280A, Anti-PD-L1 Antibody) Administered Alone or in Combination With Azacitidine in Patients With Myelodysplastic Syndromes

    ... Phase 1 study of Atezolizumab (MPDL3280A, Anti-PD-L1 antibody) monoclonal antibody [mAb] in intermediate/high/very ...

    Clinical Trial last updated 04/27/2016 - 9:57am.

  2. Robert A. Brodsky, MD

    ... from the loss of cell surface complement regulators. The monoclonal antibody eculizimab was developed to combat the thrombosis that ...

    Bio last updated 09/12/2016 - 11:04am.

  3. Safety and Effect of GL-ONC1 Administered IV With or Without Eculizumab Prior to Surgery to Patients With Solid Organ Cancers Undergoing Surgery

    ... people worldwide. Eculizumab is a type of drug called a monoclonal antibody . This drug is designed to inhibit the activity of a protein called ...

    Clinical Trial last updated 04/28/2016 - 1:57pm.

  4. Phase 1 Study to Evaluate MEDI4736 in MDS

    ... dose-escalation and dose-expansion study of MEDI4736 (a monoclonal antibody that targets programmed cell death-1 ligand 1 [PD-L1]) to evaluate ...

    Clinical Trial last updated 04/27/2016 - 12:43pm.

  5. Alemtuzumab

    ... and islet cell transplantation . It is a monoclonal antibody that binds to CD52 , a protein present on the surface of mature ...

    Drug last updated 03/26/2016 - 8:15pm.

  6. Reduced-Intensity Conditioning (RIC) and Myeloablative Conditioning (MAC) for HSCT in AML/MDS

    ... Conditioning Regimen Campath (alemtuzumab) - drug class: monoclonal antibody Droxia (hydroxyurea) - drug class: antimetabolite Fludara ...

    Clinical Trial last updated 05/03/2016 - 10:36am.

  7. Ipilimumab or Nivolumab in Treating Patients With Relapsed Hematologic Malignancies After Donor Stem Cell Transplant

    ... (relapsed) after donor stem cell transplant . Monoclonal antibodies, such as ipilimumab and nivolumab, may interfere with the ... T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody BMS-734016 MDX-010 MDX-CTLA4 Yervoy Other: Laboratory Biomarker ...

    Clinical Trial last updated 04/28/2016 - 2:18pm.

  8. Ipilimumab in Treating Patients With Relapsed or Refractory High-Risk Myelodysplastic Syndrome or Acute Myeloid Leukemia

    ... that has come back or no longer responds to treatment. Monoclonal antibodies, such as ipilimumab, may interfere with the ability of ... Names: Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody BMS-734016 MDX-010 MDX-CTLA4 Yervoy Other: Laboratory Biomarker ...

    Clinical Trial last updated 04/21/2016 - 9:26am.