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  1. CD34+ Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation for Non-Malignant Disease

    ... Unrelated donor : An 8/10, 9/10 or 10/10 matched unrelated adult donor (MUD) will be required for study entry. Related Donor: A 5/10, 6/10, 7/10, 8/10, 9/10 or 10/10 matched (or partially ...

    Clinical Trial last updated 06/13/2016 - 2:06pm.

  2. Cord Blood Transplant

    ... blood from a Human Leukocyte Antigen ( HLA ) matched sibling donor is the most commonly used source of allogeneic stem ... sibling, volunteer unrelated donors or partially mismatched related donors (PMRD), stored cord blood may be used as a source of allogeneic ...

    Clinical Trial last updated 04/27/2016 - 9:59am.

  3. Safety and Efficacy of Two Doses of ATIR101, a T-lymphocyte Enriched Leukocyte Preparation Depleted of Host Alloreactive T-cells, in Patients With a Hematologic Malignancy Who Received a Hematopoietic Stem Cell Transplantation From a Haploidentical Donor

    ... following a T-cell depleted stem cell graft from a related haploidentical donor. All patients are planned to receive two ATIR101 doses of 2×10E6 viable ... Availability of a fully matched related or unrelated donor following a donor search ...

    Clinical Trial last updated 04/29/2016 - 12:25pm.

  4. Busulfan and Cyclophosphamide Followed By ALLO BMT

    ... Acceptable stem cell sources include: HLA -matched related or unrelated donor bone marrow (6/6 or 5/6 antigen match) ...

    Clinical Trial last updated 04/29/2016 - 1:23pm.

  5. HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

    ... of cyclosporine will further reduce transplant-related side effects for patients with Fanconi Anemia (FA). Patients will undergo a transplant utilizing mis-matched related or matched unrelated donors following a preparative regimen of ...

    Clinical Trial last updated 05/09/2016 - 3:19pm.

  6. GVHD Prophylaxis With Post Transplant Cyclophosphamide for Patients With Renal Insufficiency Undergoing a Conventional 8/8 HLA-matched Related or Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplant

    ... must have a healthy HLA compatible (8/8 molecularly matched related, or unrelated) donor willing to undergo BM harvesting or PBSC apheresis ...

    Clinical Trial last updated 04/29/2016 - 12:40pm.

  7. Clinical Trials Report for February 2015

    ... currently recruiting patients. Each has a specific purpose related to aplastic anemia , MDS, or PNH. Should you consider a ... of allogenic stem cell transplantation from either a matched unrelated donor or a mismatched reacted donor using the ...

    Page last updated 01/29/2015 - 10:10am.

  8. AML Therapy With Irradiated Allogeneic Cells

    ... I antigen) human leukocyte antigen ( HLA )-matched (by serology or low resolution deoxyribonucleic acid [DNA] testing) ... ECOG performance status =< 2 DONOR: donor must be related to patient and be partially (>= 3/6 antigen) HLA-matched DONOR: ...

    Clinical Trial last updated 06/13/2016 - 3:14pm.

  9. Randomized HaploCord Blood Transplantation vs. Double Umbilical Cord Blood Transplantation for Hematologic Malignancies

    ... cord blood selection can prioritize matching and better matched donors can be identified rapidly for most subjects. ... An human leukocyte antigen ( HLA )-identical related or unrelated donor cannot be identified within an appropriate ...

    Clinical Trial last updated 04/29/2016 - 1:15pm.

  10. Allogeneic Stem Cell Transplant With Alpha/Beta T AND B Cell Depletion for Hematologic Malignancies (AB-CliniMACs)

    ... receiving alternative donor (unrelated or partially matched related) mobilized peripheral stem cells (PSCs) using the CliniMACS ...

    Clinical Trial last updated 06/06/2016 - 3:10pm.