Search | Aplastic Anemia and MDS International Foundation

Search

Search results

  1. First-line matched related donor hematopoietic stem cell transplantation compared to immunosuppressive therapy in acquired severe aplastic anemia.

    ... cells is a first-line treatment option if HLA -matched related donors are available. First-line immunosuppressive therapy may ...

    Research Article last updated 07/20/2018 - 5:14pm.

  2. Retrospective study of alemtuzumab vs ATG-based conditioning without irradiation for unrelated and matched sibling donor transplants in acquired severe aplastic anemia: a study from the British Society for Blood and Marrow Transplantation.

    ... patients received alemtuzumab and 55 ATG-based regimens. A matched sibling donor (MSD) was used in 87 (56%), matched unrelated donor (MUD) in 60 (39%) and other related or mismatched unrelated donor (UD) in 8 (5%) patients. Engraftment ...

    Research Article last updated 07/20/2018 - 5:15pm.

  3. Pilot trial of risk-adapted cyclophosphamide intensity based conditioning and HLA matched sibling and unrelated cord blood stem cell transplantation in newly diagnosed pediatric and adolescent recipients with acquired severe aplastic anemia

    ... hematopoietic stem cell transplantation (AlloHSCT) from matched related donors (MRD) has resulted in the highest survival rates in children ...

    Research Article last updated 07/20/2018 - 5:15pm.

  4. Impact of donor source on hematopoietic cell transplantation outcomes for patients with myelodysplastic syndromes (MDS)

    ... (HCT) from human leukocyte antigen ( HLA ) matched related donor (MRD) and matched unrelated donors (MUD) produces similar ...

    Research Article last updated 07/20/2018 - 5:15pm.

  5. Allogeneic transplantation for aplastic anemia

    ... Search terms included severe aplastic anemia, HLA -matched sibling, unrelated donor , hematopoietic stem cell ... older patients ranging from 50-70%. The risks of transplant-related morbidity and mortality increase with age and explain the observed ...

    Research Article last updated 07/20/2018 - 5:14pm.

  6. Unrelated cord blood transplantation in a child with very severe aplastic anemia

    ... in the absence of a human leukocyte antigen - matched related donor (MRD). For SAA patients with complications such as bacterial ...

    Research Article last updated 07/20/2018 - 5:14pm.

  7. Acquired Aplastic Anemia: What Have We Learned and What Is in the Horizon?

    ... stem cells highlights the underlying mechanism. Matched related donor allogeneic hematopoietic stem cell transplantation is the ...

    Research Article last updated 06/13/2018 - 1:56pm.

  8. Transplantation strategies for the management of patients with myelodysplastic syndromes.

    ... by the age of MDS patients, high rates of transplant-related mortality (TRM) and availability of a suitable HLA -matched donor. Results from several large centres indicated 3-year overall ...

    Research Article last updated 07/20/2018 - 5:14pm.

  9. Reduced intensity conditioning and co-transplantation of unrelated peripheral stem cells combined with umbilical cord mesenchymal stem/stroma cells for young patients with refractory severe aplastic anemia.

    ... had failed initial CSA treatment and lacked a HLA -matched sibling donor, underwent co-transplantation of unrelated donor ... primary graft failure, the reason for which may be related to a long history (>17 years) of SAA. The other four patients achieved ...

    Research Article last updated 07/20/2018 - 5:15pm.

  10. Haploidentical transplantation in patients with acquired aplastic anemia

    ... antithymocyte globulin and lacking an HLA -matched related or unrelated donor . The platforms of both ex vivo T-cell-depleted and unmanipulated ...

    Research Article last updated 07/20/2018 - 5:15pm.